Table 1.

Demographic characteristics of SEER-Medicare pancreatic cancer cases and frequency-matched controls 1992–2015a.

Pancreatic cancer casesb
ControlsFirst primaryLater primariesAll primaries
(N = 320,296)(N = 61,081)(N = 18,993)(N = 80,074)
Characteristicsn (%)n (%)n (%)n (%)
Age at diagnosis or selection, years
 66–6942,388 (13.2)8,590 (14.1)2,007 (10.6)10,597 (13.2)
 70–7471,148 (22.2)13,979 (22.9)3,808 (20.0)17,787 (22.2)
 75–7975,692 (23.6)14,253 (23.3)4,670 (24.6)18,923 (23.6)
 80–8466,048 (20.6)12,140 (19.9)4,372 (23.0)16,512 (20.6)
 85–8943,496 (13.6)7,991 (13.1)2,883 (15.2)10,874 (13.6)
 90–9417,524 (5.5)3,357 (5.5)1,024 (5.4)4,381 (5.5)
 95–994,000 (1.2)771 (1.3)229 (1.2)1,000 (1.2)
Sex
 Men144,484 (45.1)26,277 (43.0)9,844 (51.8)36,121 (45.1)
 Women175,812 (54.9)34,804 (57.0)9,149 (48.2)43,953 (54.9)
Race/ethnicity
 Non-Hispanic white264,161 (82.5)49,619 (81.2)16,171 (85.1)65,790 (82.2)
 Non-Hispanic black23,841 (7.4)6,179 (10.1)1,705 (9.0)7,884 (9.8)
 Non-Hispanic Asian14,483 (4.5)2,176 (3.6)442 (2.3)2,618 (3.3)
 Hispanic7,893 (2.5)1,227 (2.0)237 (1.2)1,464 (1.8)
 Other/missing9,918 (3.1)1,880 (3.1)438 (2.3)2,318 (2.9)
Calendar year of diagnosis or selection
 1992–200061,352 (19.2)12,382 (20.3)2,956 (15.6)15,338 (19.2)
 2001–200573,460 (22.9)14,279 (23.4)4,086 (21.5)18,365 (22.9)
 2006–200971,592 (22.4)13,537 (22.2)4,361 (23.0)17,898 (22.4)
 2010–2015113,892 (35.6)20,883 (34.2)7,590 (40.0)28,473 (35.6)
Months of coverage, median (IQR)
 Part A/B/non-HMO67 (42–82)71 (42–84)74 (48–85)72 (43–84)
 Part D18 (0–52)17 (0–48)15 (0–49)16 (0–49)
Average physician visits/6 months, median (IQR)3.0 (1.3–5.5)3.1 (1.4–5.8)4.3 (2.3–7.1)3.4 (1.5–6.1)
Low-income subsidy/Medicaid eligibility
 Ever37,034 (11.6)6,695 (11.0)1,720 (9.1)8,415 (10.5)
 Never130,922 (40.9)24,398 (39.9)9,176 (48.3)33,574 (41.9)
 Unknown152,340 (47.6)29,988 (49.1)8,097 (42.6)38,085 (47.6)
Co-morbidities diagnoses
 Overweight or obesity17,980 (5.6)4,113 (6.7)1,398 (7.4)5,511 (6.9)
 Smoking behavior-relatedc23,803 (7.4)5,787 (9.5)2,472 (13.0)8,259 (10.3)
 Chronic obstructive pulmonary disease59,294 (18.5)12,734 (20.8)4,705 (24.8)17,439 (21.8)
 Alcohol-relatedd14,294 (4.5)4,102 (6.7)1,475 (7.8)5,577 (7.0)
 Acute or chronic pancreatitis3,609 (1.1)1,685 (2.8)591 (3.1)2,276 (2.8)
 Type 2 diabetes mellitus90,232 (28.2)21,993 (36.0)7,149 (37.6)29,142 (36.4)
Hemochromatosis653 (0.2)137 (0.2)49 (0.3)186 (0.2)
Sideroblastic anemia993 (0.3)192 (0.3)108 (0.6)300 (0.4)
Congenital dyserythropoietic anemia1,375 (0.4)262 (0.4)136 (0.7)398 (0.5)
NACLD3,316 (1.0)791 (1.3)311 (1.6)1,102 (1.4)
 Liver cirrhosis1,113 (0.3)279 (0.5)105 (0.6)384 (0.5)
 Fatty liver disease1,503 (0.5)359 (0.6)146 (0.8)505 (0.6)
  • Abbreviations: HMO, health maintenance organizations; IQR, interquartile range; NACLD, non–alcoholic-related chronic liver disease; SEER, Surveillance, Epidemiology, and Ends Results Program.

  • aControls were frequency matched to the pancreatic cancer cases by age category (66–69. 70–74, 75–79, 80–84, 85–89, 90–94, and 95–99), sex, and calendar year of diagnosis. International Classification of Diseases – 9th edition included: hemochromatosis (275.0, 275.01, and 275.03), sideroblastic (285.0), and congenital dyserythropoietic (285.8) anemias and NACLD (571.4, 571.41, 571.42, 571.49, 571.5, 571.6, 571.8, and 571.9).

  • bFirst primary pancreatic cancer was defined as pancreatic cancer occurring as a first malignancy and later primaries pancreatic cancer were defined as primary pancreatic cancer occurring as second or third malignancy between 1992 and 2015.

  • cAny personal history of tobacco use or nondependent tobacco use disorder.

  • dAny diagnosis of alcohol-induced liver disorders, alcohol-induced psych/neurologic disorders, alcohol intoxication, nondependent alcohol abuse, or personal history of alcoholism.