Table 1.

EDRN biospecimen reference sets.

Reference setType of specimensParticipants, nParticipant groups
Bladder cancerSerum, whole urine, DNA from blood497Bladder cancer cases
Healthy controls
High-risk controls
Breast cancerSerum, plasma, buffy coat832Prediagnosis specimens
DCIS cases
Invasive cancer cases
LCIS cases
Benign→later cancer cases
Normal→later cancer cases
Benign disease atypia controls
Benign disease non-atypia controls
Normal controls
Cancers in women endometrium, ovary, breastSerum, plasma536Cases (pooled)
Controls (pooled)
Colon cancerSerum, plasma, whole urine150Cases
Adenoma controls
Normal controls
Liver cancerSerum, plasma871Cases
Controls
Lung cancerSerum, plasma1,205Cases
Controls
High-risk controls with CT nodule
High-risk controls with no CT nodule
Pancreatic cancerSerum, plasma255Cases
Controls
Prostate cancerSerum, plasma, buffy coat, RNA, supernatant fluid, whole urine900Initial biopsy w/cancer cases
Repeat biopsy w/cancer cases
Confirmed but no biopsy controls
Initial biopsy w/o cancer controls
Repeat biopsy w/o cancer controls
Prostate cancer (retrospective)Serum663Cases
Controls
  • Abbreviations: DCIS, ductal carcinoma in situ; LCIS, lobular carcinoma in situ.