Table 3.

Approximate calculated relationship between mutant allele fraction and tumor characteristics.a

Mutant allele fractionb, %Tumor diameter, mmTumor weight (g) or volume (mL)
158100
0.12710
0.01131
0.005100.5
0.002580.25
0.001260.13
0.000650.06
  • aData modified from ref. 13.

  • bMAF = ratio of ctDNA and cfDNA, expressed as a percentage.