Table 2.

Incidence ratio of cancers in adult relatives of patients with pediatric cancer.

MenWomenSHAll relatives
nSIR95% CISIR95% CIPSIR95% CI
Any cancer2,3601.11a1.05–1.171.030.97–1.090.231.07a1.03–1.11
Prostate3351.11a0.99–1.231.11a0.99–1.23
Breast3071.060.13–3.820.970.87–1.090.980.970.87–1.09
Lung1761.120.91–1.361.35a1.07–1.690.411.21a1.04–1.40
Pharynx161.66a0.91–2.780.610.07–2.201.360.78–2.22
Esophagus281.56a0.95–2.401.690.73–3.340.951.59a1.06–2.30
Stomach801.120.82–1.481.33b0.91–1.880.601.19b0.95–1.49
Colon1841.040.82–1.301.31a1.07–1.590.291.18a1.01–1.36
Bile duct/gallbladder331.88a1.08–3.061.140.66–1.830.411.41a0.97–1.98
Pancreas631.260.87–1.761.180.79–1.690.831.22b0.94–1.56
Kidney690.940.65–1.321.57a1.10–2.170.161.19b0.93–1.51
Urinary tract1111.18b0.95–1.450.720.44–1.110.131.060.87–1.28
Hodgkin181.73a0.90–3.031.200.44–2.620.641.51b0.90–2.39
  • Note: Prostate, breast, and lung cancer and cancer types with at least one P value <0.1 are presented.

  • Abbreviation: SH, sex heterogeneity.

  • aP < 0.05.

  • bP < 0.1.