Table 3.

Unadjusted and adjusted overall survival for patients with locoregional disease.

UnadjustedAdjusteda
HR (95% CI)HR (95% CI)
Sex
 MaleReferenceReference
 Female0.84 (0.62–1.14)0.61 (0.35–1.08)
Age at diagnosis
 0–390.13 (0.06–0.26)0.22 (0.09–0.52)
 40–640.35 (0.24–0.50)0.48 (0.28–0.81)
 ≥65ReferenceReference
Year of diagnosis
 1987–2007ReferenceReference
 2008–20160.98 (0.64–1.50)0.83 (0.44–1.54)
Primary tumor location
 Lower extremityReferenceReference
 Upper extremity0.75 (0.42–1.32)0.97 (0.44–2.12)
 Abdomen/trunk1.14 (0.77–1.70)1.08 (0.60–1.94)
 Head/neck2.58 (1.24–5.38)3.32 (0.96–11.45)
Tumor gradeb
 IReferenceReference
 II2.32 (1.14–4.76)1.61 (0.73–3.55)
 III3.28 (1.40–7.69)2.64 (1.07–6.52)
 IV4.48 (1.91–10.54)3.33 (1.23–9.06)
Tumor sizeb
 ≤5 cmReferenceReference
 >5 cm2.02 (1.33–3.07)2.09 (1.10–3.99)
Chemotherapy
 No/unknownReferenceReference
 Yes1.90 (1.11–3.27)1.76 (0.75–4.15)
Surgery
 NoReferenceReference
 Yes0.27 (0.16–0.47)0.41 (0.13–1.27)
Radiation
 No/unknownReferenceReference
 Yes1.45 (1.03–2.06)1.04 (0.62–1.74)
  • aCases with missing data were excluded from adjusted model (n = 192).

  • bTumor grade n = 208; tumor size n = 332 (among LRD).