Table 2.

Baseline characteristics and blood indices of men free from prostate cancer and men who developed prostate cancer.

All men (n = 209,686)Men who developed prostate cancer (n = 5,723)
Sociodemographic
 Age at recruitment (years), mean (SD)56.6 (8.2)62.2 (5.2)
 Most deprived quintile, % (n)19.8 (41,514)15.7 (896)
 Black ethnicity, % (n)1.5 (3,083)2.0 (117)
 Not in paid/self-employment, % (n)38.7 (81,179)57.1 (3,268)
 Living with partner, % (n)76.3 (160,064)79.2 (4,533)
Anthropometric, mean (SD)
 Height (cm)175.6 (6.8)175.1 (6.7)
 BMI (kg/m2)27.8 (4.2)27.6 (3.8)
Lifestyle, % (n)
 Current cigarette smokers12.4 (26,061)9.2 (524)
 Drinking alcohol ≥20 g per day43.3 (90,834)42.5 (2,432)
 Low physical activity (0–10 METs per week)27.4 (57,517)26.2 (1,500)
Health history, % (n)
 Hypertension52.2 (109,380)59.0 (3,376)
 Diabetes6.9 (14,434)6.0 (342)
Prostate-specific factors, % (n)
 Ever had a PSA test27.8 (58,279)45.9 (2,624)
 Family history of prostate cancer7.5 (15,750)13.0 (745)
Blood measures at initial assessment, median (interquartile range)
 Red blood cell
  Red blood cell count (1012 cells/L)4.75 (4.51–4.99)4.73 (4.49–4.98)
  Red blood cell distribution width (%)13.3 (12.9–13.8)13.4 (13.0–13.9)
  Hematocrit (%)43.4 (41.5–45.2)43.3 (41.4–45.3)
  Hemoglobin concentration (g/dL)15.0 (14.4–15.7)15.0 (14.3–15.6)
  MCV (fL)91.4 (88.8–94.1)91.5 (88.9–94.2)
  MCH (pg)31.7 (30.7–32.7)31.7 (30.7–32.6)
  MCHC (g/dL)34.6 (34.0–35.2)34.5 (33.9–35.2)
  MSCV (fL)82.5 (79.2–85.9)82.6 (79.4–86.1)
  Reticulocyte count (1012 cells/L)0.06 (0.05–0.08)0.06 (0.05–0.08)
 Platelet
  Platelet count (109 cells/L)234 (202–269)233 (200–269)
  Platelet distribution width (%)16.5 (16.2–16.9)16.5 (16.2–16.9)
  Mean platelet volume (fL)9.18 (8.54–9.90)9.17 (8.53–9.93)
 White blood cell
  White blood cell count (109 cells/L)6.69 (5.67–7.90)6.70 (5.70–7.89)
  Neutrophil count (109 cells/L)4.06 (3.29–5.00)4.15 (3.36–5.09)
  Eosinophil count (109 cells/L)0.15 (0.10–0.24)0.15 (0.09–0.24)
  Basophil count (109 cells/L)0.029 (0.019–0.044)0.028 (0.019–0.043)
  Monocyte count (109 cells/L)0.49 (0.39–0.61)0.50 (0.40–0.62)
  Lymphocyte count (109 cells/L)1.81 (1.47–2.21)1.78 (1.45–2.18)
  • Abbreviation: MET, metabolic equivalent.