Summary description of hematologic parameters and measurement/calculation methods by UK Biobank.
| Hematologic parameter | Description | Measurement/calculation |
|---|---|---|
| Red blood cell | ||
| Red blood cell count (1012 cells/L) | Number of red blood cells in the sample | Measured |
| Red blood cell distribution width (%) | Spread of red blood cell population | Deriveda |
| Hematocrit (%) | Volume occupied by red blood cells in the blood | (MCV × RBC)/10 |
| Hemoglobin concentration (g/dL) | Total hemoglobin concentration in sample | Measured |
| MCV (fL) | Average volume of red blood cells | Deriveda |
| MCH (pg) | Mass of hemoglobin in the average red blood cell | (HGB/RBC) × 10 |
| MCHC (g/dL) | Average mass of hemoglobin per the relative volume of red blood cells in the whole blood sample | (HGB/HCT) × 100 |
| Reticulocyte count (1012 cells/L) | Number of reticulocytes in the red blood cell sample | % Reticulocyte × RBC |
| Platelet | ||
| Platelet count (109 cells/L) | Number of platelets in the sample | Measured |
| Platelet distribution width (%) | Variation in platelet volume | Deriveda |
| Mean platelet volume (fL) | Average volume of individual platelets in the sample | Deriveda |
| White blood cell | ||
| White blood cell count (109 cells/L) | Number of white blood cells in the sample | Measured |
| Neutrophil count (109 cells/L) | Number of neutrophils in the white blood cell sample | (% Proportion of neutrophils/100) × WBC |
| Eosinophil count (109 cells/L) | Number of eosinophils in the white blood cell sample | (% Proportion of eosinophils/100) × WBC |
| Basophil count (109 cells/L) | Number of basophils in the white blood cell sample | (% Proportion of basophils/100) × WBC |
| Monocyte count (109 cells/L) | Number of monocytes in the white blood cell sample | (% Proportion of monocytes/100) × WBC |
| Lymphocyte count (109 cells/L) | Number of lymphocytes in the white blood cell sample | (% Proportion of lymphocytes/100) × WBC |
Note: Measurement/calculation methods were obtained from: http://biobank.ndph.ox.ac.uk/showcase/showcase/docs/haematology.pdf.
Abbreviations: HCT, hematocrit; HGB, hemoglobin concentration; RBC, red blood cell count; WBC, white blood cell count.
↵aDerived values were calculated within the instrument using multiple scatterplots and histograms for each sample.