Table 1.

Summary description of hematologic parameters and measurement/calculation methods by UK Biobank.

Hematologic parameterDescriptionMeasurement/calculation
Red blood cell
 Red blood cell count (1012 cells/L)Number of red blood cells in the sampleMeasured
 Red blood cell distribution width (%)Spread of red blood cell populationDeriveda
 Hematocrit (%)Volume occupied by red blood cells in the blood(MCV × RBC)/10
 Hemoglobin concentration (g/dL)Total hemoglobin concentration in sampleMeasured
 MCV (fL)Average volume of red blood cellsDeriveda
 MCH (pg)Mass of hemoglobin in the average red blood cell(HGB/RBC) × 10
 MCHC (g/dL)Average mass of hemoglobin per the relative volume of red blood cells in the whole blood sample(HGB/HCT) × 100
 Reticulocyte count (1012 cells/L)Number of reticulocytes in the red blood cell sample% Reticulocyte × RBC
Platelet
 Platelet count (109 cells/L)Number of platelets in the sampleMeasured
 Platelet distribution width (%)Variation in platelet volumeDeriveda
 Mean platelet volume (fL)Average volume of individual platelets in the sampleDeriveda
White blood cell
 White blood cell count (109 cells/L)Number of white blood cells in the sampleMeasured
 Neutrophil count (109 cells/L)Number of neutrophils in the white blood cell sample(% Proportion of neutrophils/100) × WBC
 Eosinophil count (109 cells/L)Number of eosinophils in the white blood cell sample(% Proportion of eosinophils/100) × WBC
 Basophil count (109 cells/L)Number of basophils in the white blood cell sample(% Proportion of basophils/100) × WBC
 Monocyte count (109 cells/L)Number of monocytes in the white blood cell sample(% Proportion of monocytes/100) × WBC
 Lymphocyte count (109 cells/L)Number of lymphocytes in the white blood cell sample(% Proportion of lymphocytes/100) × WBC
  • Note: Measurement/calculation methods were obtained from: http://biobank.ndph.ox.ac.uk/showcase/showcase/docs/haematology.pdf.

  • Abbreviations: HCT, hematocrit; HGB, hemoglobin concentration; RBC, red blood cell count; WBC, white blood cell count.

  • aDerived values were calculated within the instrument using multiple scatterplots and histograms for each sample.