Table 3.

Change (percent relative difference) in serum biomarkers from baseline to 6 months dichotomized by <10% vs. >10% weight loss from baseline to 6 months (n = 138).

<10% weight loss at 6 months (n = 29)>10% weight loss at 6 months (n = 109)
Median relative difference, %P value between groupsa
Adiponectin (μg/mL)316b0.060
Leptin (ng/mL)−38b−68b<0.0001
A/L ratio62c284b<0.0001
PAI-1 (ng/mL)−9d−22b0.0007
Insulin (pg/mL)−30d−42b0.0027
IL-6 (pg/mL)−5−110.69
HGF (pg/mL)−11−70.50
TNFα (pg/mL)1−10.77
  • Note: Significant change within group by nonparametric Wilcoxon test.

  • aNonparametric Mann–Whitney test.

  • bP < 0.0001.

  • cP < 0.001.

  • dP < 0.006.