Table 4.

Association between tomato intake (g/day) and HCC by HBsAg serology, Singapore Chinese Health Study, 1993–2015.

CasesControlsOR (95% CI)
Tomato intake overalla
 First quartile (<1.95)631041.00a
 Second quartile (1.95–4.81)401080.51 (0.28–0.93)
 Third quartile (4.81–8.83)571300.58 (0.33–1.03)
 Fourth quartile (≥8.83)371230.52 (0.29–0.94)
Ptrend0.0409
Tomato intake stratified by HBV status
HBsAg (−)
 First quartile (<1.95)411001.00b
 Second quartile (1.95–4.81)261010.56 (0.30–1.02)
 Third quartile (4.81–8.83)331270.54 (0.30–0.96)
 Fourth quartile (≥8.83)271180.51 (0.28–0.94)
Ptrend0.0300
HBsAg (+)
 First quartile (<1.95)2241.00b
 Second quartile (1.95–4.81)1470.21 (0.04–1.21)
 Third quartile (4.81–8.83)2430.90 (0.14–5.79)
 Fourth quartile (≥8.83)1050.29 (0.05–1.64)
Ptrend0.3590
Pinteraction, HBsAg and tomato intake0.75
  • aConditional logistic regression that retained case–control pairs where controls were matched to cases on age, gender, date of interview, dialect group, and date of sample collection. Model was adjusted for BMI, education, smoking status, alcohol intake, diabetes status, physical activity, total energy intake, and HBsAg serology.

  • bUnconditional logistic regression adjusted for age, gender, dialect, education, BMI, smoking status, alcohol intake, year of enrollment, diabetes status, physical activity, and total energy intake.