Table 4.

Comparison of the incidence of other cancers by dengue virus infection status.

Dengue cohortNon-dengue cohort
CanceraNo. of eventsIncidence rate (per 100,000 person-years)No. of eventsIncidence rate (per 100,000 person-years)Crude HR (95% CI)PAdjusted HRb (95% CI)PAdjusted SHRb (95% CI)P
All lymphoma1614.487513.691.06 (0.62–1.81)0.8390.87 (0.51–1.52)0.6320.89 (0.51–1.56)0.680
Nasopharynx98.14427.661.06 (0.52–2.18)0.8681.21 (0.58–2.52)0.6201.28 (0.58–2.56)0.604
Esophagus119.958715.870.63 (0.33–1.17)0.1440.60 (0.32–1.14)0.1190.61 (0.33–1.15)0.128
Stomach3228.9816129.390.99 (0.67–1.44)0.9400.96 (0.65–1.42)0.8290.98 (0.66–1.46)0.930
Colon, rectum, and anus127115.33562102.851.12 (0.92–1.36)0.2471.09 (0.89–1.32)0.4201.11 (0.91–1.36)0.318
Liver and intrahepatic bile ducts9081.5753998.500.83 (0.66–1.04)0.0970.84 (0.67–1.05)0.1290.86 (0.68–1.08)0.193
Lung, trachea, and bronchus11099.6852996.651.03 (0.84–1.27)0.7720.96 (0.77–1.18)0.6850.98 (0.79–1.21)0.831
Female breast66118.14366132.080.89 (0.69–1.16)0.4010.84 (0.64–1.10)0.1990.85 (0.65–1.11)0.228
Cervix814.266724.070.59 (0.29–1.23)0.1610.57 (0.27–1.21)0.1430.58 (0.28–1.21)0.146
Prostate5295.9620074.401.29 (0.95–1.75)0.1041.13 (0.82–1.56)0.4541.16 (0.83–1.62)0.380
  • Abbreviations: No., number; SHR, subdistribution HR.

  • aResults for brain tumors were not reported because results of fewer than three individuals were not allowed to be exported under the regulations of HWDC in Taiwan.

  • bAdjusted for age, sex, area of residence, urbanization level, monthly income level, and comorbidities.