Table 3.

Relative risk of PLC for the HCV cohort, expressed as SIRs and stratified by estimated years with HCV infection.

Years with HCV infectionPerson-yearsExpectedObservedSIR95% CI
<1052,6790.4615(5–30)
10–20117,0181.564(1.4–8.6)
20–2589,9602.84516(11.8–21.7)
25–30102,9694.819040(34.1–45.6)
30–3593,4878.341150(45.0–54.8)
35–4057,7256.144573(65.9–79.5)
40–4521,9373.621961(53.0–69.3)
45+2,5740.72840(25.2–54.8)
Total538,34828.2135048(45.2–50.3)
  • Note: The reference population was the matched non-HCV comparison cohort. Test for homogeneity of SIR: 230, P < 0.0001. Test for trend in SIR: 159.9, P < 0.0001.