Variables collected in the VIRUSCAN Study, Tampa, FL, 2014–2018.
| Source | Variable details | Visit |
|---|---|---|
| Study questionnaire | B | |
| Demographics | Gender, age, race, ethnicity, education level, marital status, place of birth | |
| Sun protection | Use of sunscreen, long sleeves, pants, hats, sunglasses, and sun avoidance | |
| Sun exposures | Occupational sun exposure, history of sunburn, skin reaction to the sun, use of sun lamps or UV nail dryers | |
| Phenotypic factors | Eye color, hair color, untanned skin color, number of moles on arm/body | |
| Skin cancer screening | Number of skin exams per year | |
| Skin conditions | History of skin biopsies, eczema, psoriasis, acne, vitiligo, actinic keratosis, keratoacanthoma, warts, other skin conditions, treatment for skin conditions | |
| Cancer history | Melanoma, basal cell carcinoma, squamous cell carcinoma, other skin cancers or other cancers | |
| Other medical conditions | Organ transplant, Crohn's disease, type 1 diabetes, type 2 diabetes, heart disease, epidermodysplasia verruciformis, lupus, multiple sclerosis, Sezary syndrome, rheumatoid arthritis, osteoarthritis, xeroderma pigmentosum, asthma/bronchitis/emphysema, gout | |
| Smoking and alcohol | Smoking and drinking habits | |
| Steroid medication | Use of oral steroids or steroid creams | |
| Clinical findings of total body skin examinations | Identification of premalignant (actinic keratosis) and malignant lesions [tumor histology, anatomic site (head, neck, torso, arms, legs)] | B and FU |
| Biospecimens | ||
| Blood | HPV/HPyV serum antibodies | B |
| Eyebrow hair | HPV/HPyV viral DNA | B and FU |
| Skin swabs | HPV/HPyV viral DNA | B and FU |
| Tumor tissue | HPV/HPyV viral DNA, solar elastosis, papillomatosis, hypergranulosis, and crateriform architecture (SCC only) | B and FU |
| Spectrophotometer | Inner upper arm, forearm, and forehead spectrophotometer reading | B and FU |
| Sun exposure questionnaire | (subsample n = 159) | FU |
| Sun exposure (past week) | Time outdoors, frequency of sunbathing and spending time in the sun sitting or lying | |
| Sun protection (past week) | Use of sunscreen, clothing, hat and sun avoidance |
Abbreviations: B, baseline visit; FU, follow-up visit.