Table 2.

Leading cancer sites for American Indians/Alaska Nativesa compared with non-Hispanic whites for the United States, females, all ages, PRCDA counties, USA, 2010 to 2015

OverallNorthern PlainsAlaskaSouthern PlainsPacific CoastEastSouthwest
SiteRankbAI/AN (W)AI/AN(W) ratecRRdRankbAI/AN (W)AI/AN(W) ratecRRdRankbAI/AN (W)AI/AN(W) ratecRRdRankbAI/AN (W)AI/AN(W) ratecRRdRankbAI/AN (W)AI/AN(W) ratecRRdRankbAI/AN (W)AI/AN(W) ratecRRdRankbAI/AN (W)AI/AN (W) ratecRRd
Female breast1 (1)112.5 (129.9)0.87e1 (1)128.4 (122.7)1.051 (1)156.2 (124.1)1.26e1 (1)151.1 (116.1)1.30e1 (1)124.3 (133.9)0.93e1 (1)83.6 (136.4)0.61e1 (1)68.3 (120.6)0.57e
Lung and bronchus2 (2)58.6 (55.4)1.06e2 (2)104.0 (53.9)1.93e3 (2)73.5 (51.8)1.42e2 (2)87.3 (56.9)1.53e2 (2)63.0 (52.7)1.20e2 (2)42.0 (61.5)0.68e6 (2)15.9 (48.7)0.33e
Colon and rectum3 (3)45.4 (33.1)1.37e3 (3)51.3 (33.9)1.51e2 (3)92.8 (32.3)2.87e3 (3)57.9 (34.8)1.66e3 (3)44.6 (32.5)1.37e3 (3)30.2 (34)0.892 (3)28.8 (30.6)0.94
Corpus and uterus, NOS4 (4)26.7 (25.9)1.034 (4)25.2 (28.4)0.896 (4)18.2 (26.5)0.68e4 (4)29.4 (21.5)1.37e4 (5)29.3 (25.9)1.134 (4)19.0 (27.3)0.70e3 (5)27.7 (22.1)1.25e
Kidney and renal pelvis5 (11)20.0 (10.8)1.85e5 (9)23.4 (11.1)2.11e5 (10)21.6 (10.9)1.98e5 (8)27.9 (12.6)2.21e7 (11)15.5 (10.3)1.51e5 (12)12.6 (11.3)1.125 (11)17.1 (9.5)1.81e
Thyroid6 (5)17.9 (22.5)0.80e7 (6)16.0 (19.3)0.83e4 (6)24.6 (15.6)1.58e6 (5)21.0 (18.9)1.15 (6)18.3 (20.1)0.917 (5)9.2 (25.7)0.36e4 (4)17.3 (25.8)0.67e
Non-Hodgkin lymphoma7 (7)15.0 (15.9)0.956 (7)16.4 (16.6)0.998 (7)14.5 (14.4)1.017 (7)19.5 (14.6)1.34e6 (7)17.1 (15.7)1.096 (7)10.2 (16.8)0.60e9 (7)11.1 (13.7)0.81e
Ovary8 (8)12.6 (11.8)1.068 (8)12.8 (11.1)1.1512 (8)8.8 (12.6)0.79 (9)15 (11.5)1.30e10 (8)10.7 (12.2)0.8815 (8)6.3 (12.0)0.52e7 (8)14.4 (11.4)1.26e
Pancreas9 (10)11.6 (10.8)1.0710 (11)12.5 (10.6)1.189 (9)13.8 (11.1)1.258 (11)15.7 (10.0)1.58e13 (10)10.2 (10.7)0.9510 (10)7.2 (11.4)0.63e10 (9)9.6 (9.8)0.99
Cervix10 (14)11.2 (6.6)1.69e9 (14)12.7 (6.2)2.04e11 (13)10.4 (6.3)1.65e10 (12)13.9 (8.4)1.65e8 (14)15.1 (6.9)2.19e9 (14)7.8 (6.4)1.2113 (13)7.2 (6.3)1.14
Liver and intrahepatic bile duct11 (17)10.5 (3.4)3.08e12 (18)10.5 (3.1)3.43e16 (17)6.5 (3.2)2.02e12 (17)9.5 (3.5)2.71e9 (17)10.8 (3.7)2.90e11 (18)7.2 (3.3)2.20e8 (17)12.5 (3.4)3.71e
Leukemias12 (9)10.0 (11.0)0.91e11 (10)12.2 (11.0)1.1114 (12)8.0 (10.2)0.7811 (10)13.2 (10.8)1.23e11 (9)10.5 (10.9)0.9712 (9)6.9 (11.8)0.59e12 (10)7.6 (9.8)0.77e
Stomach13 (18)7.5 (3.3)2.29e15 (17)6.2 (3.1)1.98e7 (18)16.3 (2.9)5.55e16 (18)6.0 (2.8)2.14e17 (18)4.8 (3.1)1.56e8 (17)8.1 (3.9)2.08e11 (18)9.1 (2.7)3.36e
Oral cavity and pharynx14 (13)6.9 (6.8)1.0213 (13)10.5 (6.7)1.55e10 (15)13.7 (5.5)2.49e15 (14)6.3 (6.9)0.914 (13)8.4 (7.0)1.2114 (13)6.8 (7.2)0.9317 (15)3.4 (5.6)0.62e
Melanomas of the skin15 (6)6.7 (22.4)0.30e19 (5)3.8 (20.2)0.19e15 (5)7.4 (16.0)0.46e13 (6)9.1 (15.4)0.59e12 (4)10.3 (26.8)0.38e13 (6)6.8 (22.3)0.31e16 (6)4.0 (18.8)0.21e
  • NOTE: Years of data and registries used: 1999–2015 (48 states): AK*, AL*, AZ*, CA*, CO*, CT*, DE, DC, FL*, GA, HI, IA*, ID*, IL, IN*, KS*, KY, LA*, MA*, MD, ME*, MI*, MN*, MO, MT*, ND* NE*, NH, NJ, NM*, NV*, NY*, NC*, OH, OK*, OR*, PA*, RI*, SC*, TX*, TN, UT*, VT, VA, WA*, WI*, WV, WY*; 2000–2015: AR, SD*; 2003–2015: MS*. *States with at least one county designated as PRCDA.

  • Percent regional coverage of AI/AN in PRCDA counties to AI/AN in all counties: Northern Plains = 54.2%; Alaska = 100%; Southern Plains = 56.5%; Southwest = 83.8%; Pacific Coast = 60.2%; East = 16.4%; Total US = 53.0%.

  • Source: Cancer registries in the Centers for Disease Control and Prevention's NPCR and/or the NCI's SEER Program.

  • Abbreviations: NOS, not otherwise specified; W, non-Hispanic white.

  • aAI/AN race is reported by NPCR and SEER registries or through linkage with the IHS patient registration database. Includes only AI/AN of non-Hispanic origin.

  • bRank based on rates. AI/AN (white).

  • cRates are per 100,000 persons and are age-adjusted to the 2000 U.S. standard population (19 age groups - Census P25-1130).

  • dRRs are AI/AN versus white and are calculated in SEER*Stat prior to rounding of rates and may not equal RRs calculated from rates presented in the table.

  • eIndicates RR is statistically significant (P < 0.05).