Table 1.

Leading cancer sites for American Indians/Alaska Nativesa compared with non-Hispanic whites for the United States, males, all ages, PRCDA counties, USA, 2010 to 2015

OverallNorthern PlainsAlaskaSouthern PlainsPacific CoastEastSouthwest
Cancer siteRankbAI/AN (W)AI/AN(W) ratecRRdRankbAI/AN (W)AI/AN(W) ratecRRdRankb,AI/AN (W)AI/AN(W) ratecRRdRankbAI/AN (W)AI/AN(W) ratecRRdRankbAI/AN (W)AI/AN(W) ratecRRdRankbAI/AN (W)AI/AN(W) ratecRRdRankbAI/AN (W)AI/AN (W) ratecRRd
Prostate1 (1)86.7 (105.4)0.82e2 (1)110.7 (106.8)1.043 (1)58.2 (90.0)0.65e1 (1)116.8 (99.2)1.18e1 (1)81.3 (105.8)0.77e1 (1)71.4 (113.5)0.63e1 (1)64.3 (89.7)0.72e
Lung and bronchus2 (2)76.4 (68.2)1.12e1 (2)122.4 (68.9)1.77e1 (2)118.4 (60.1)1.97e2 (2)115.9 (83.7)1.38e2 (2)72.6 (62.0)1.17e2 (2)49.8 (76.4)0.65e4 (2)24.3 (56.9)0.43e
Colon and rectum3 (3)57.5 (42.3)1.36e3 (3)71.7 (43.0)1.67e2 (3)95.6 (39.2)2.44e3 (3)71.9 (46.3)1.56e3 (3)48.5 (41.2)1.18e3 (4)39.9 (44.1)0.902 (3)42.4 (38.7)1.10
Kidney and renal pelvis4 (7)35.7 (21.5)1.66e4 (7)46.4 (21.7)2.14e5 (5)27.2 (21.3)1.284 (6)43.2 (23)1.87e5 (7)27.4 (20.9)1.31e5 (7)18.8 (23.1)0.813 (7)37.2 (18.7)1.99e
Liver and intrahepatic bile duct5 (11)22.9 (10.0)2.30e6 (15)24.3 (7.7)3.17e9 (11)17.3 (10.4)1.67e8 (11)22.0 (9.9)2.24e4 (11)27.9 (11.1)2.53e4 (11)18.8 (10.8)1.74e5 (11)21.3 (8.3)2.58e
Urinary bladder6 (4)21.3 (39.8)0.53e5 (4)24.9 (38.2)0.65e7 (4)25.6 (38.3)0.67e5 (4)32.7 (35.7)0.926 (5)26.0 (39.0)0.67e7 (3)15.0 (44.1)0.34e12 (4)8.2 (35.3)0.23e
Non-Hodgkin lymphoma7 (6)18.7 (23.3)0.80e7 (6)20.8 (24.1)0.868 (6)20.1 (20.6)0.986 (7)28.0 (22.0)1.27e7 (6)20.7 (23.7)0.8710 (6)9.4 (24.6)0.38e8 (6)11.7 (19.4)0.60e
Oral cavity and pharynx8 (9)17.7 (18.4)0.968 (9)20.0 (17.1)1.176 (8)25.7 (15.2)1.69e7 (8)23.7 (20.4)1.168 (8)19.5 (19.1)1.026 (9)15.8 (19.3)0.8211 (9)9.1 (16.0)0.57e
Leukemia9 (8)14.4 (18.5)0.78e9 (8)16.8 (18.9)0.8911 (9)14.6 (14.4)1.0210 (9)18.5 (17.3)1.079 (9)15.1 (18.2)0.838 (8)12.9 (20.0)0.64e9 (8)9.8 (16.1)0.61e
Pancreas10 (10)14.1 (14.1)1.0011 (10)14.1 (13.9)1.0110 (10)15.3 (13.1)1.1611 (10)16.1 (13.0)1.24e10 (10)15.0 (14.0)1.079 (10)10.0 (15.3)0.65e7 (10)12.6 (12.9)0.98
Stomach11 (15)13.9 (7.6)1.83e10 (14)15.4 (7.8)1.97e4 (14)28.2 (7.2)3.93e12 (14)11.4 (6.9)1.64e13 (14)8.5 (7.5)1.1311 (15)9.4 (8.6)1.106 (16)17.0 (6.0)2.84e
Melanoma of the skin12 (5)10.0 (34.1)0.29e15 (5)8.7 (27.1)0.32e18 (7)3.8 (18.7)0.20e9 (5)19.8 (27)0.73e11 (4)10.4 (39.5)0.26e12 (5)6.4 (35.1)0.18e15 (5)5.3 (31.8)0.17e
Myeloma13 (16)8.6 (7.2)1.20e14 (13)10.4 (7.8)1.3417 (16)6.6 (5.6)1.1813 (15)9.9 (6.6)1.50e16 (16)6.5 (7.2)0.9115 (16)4.5 (7.8)0.5710 (17)9.8 (5.8)1.68e
Esophagus14 (13)8.1 (8.4)0.9613 (11)10.9 (8.9)1.2312 (12)12.2 (9)1.3614 (13)9.4 (7.7)1.2314 (13)7.7 (8.4)0.9214 (14)5.4 (8.7)0.6314 (14)5.8 (7.9)0.73e
Testis15 (17)6.9 (7.0)0.9816 (16)7.4 (7.3)1.0113 (15)8.5 (6.8)1.2518 (18)5.8 (5.6)1.0412 (15)8.5 (7.4)1.1513 (17)5.6 (7.2)0.7813 (15)6.4 (6.2)1.03
  • NOTE: Years of data and registries used: 1999–2015 (48 states): AK*, AL*, AZ*, CA*, CO*, CT*, DE, DC, FL*, GA, HI, IA*, ID*, IL, IN*, KS*, KY, LA*, MA*, MD, ME*, MI*, MN*, MO, MT*, ND* NE*, NH, NJ, NM*, NV*, NY*, NC*, OH, OK*, OR*, PA*, RI*, SC*, TX*, TN, UT*, VT, VA, WA*, WI*, WV, WY*; 2000–2015: AR, SD*; 2003–2015: MS*. *States with at least one county designated as PRCDA.

  • Percent regional coverage of AI/AN in PRCDA counties to AI/AN in all counties: Northern Plains = 54.2%; Alaska = 100%; Southern Plains = 56.5%; Southwest = 83.8%; Pacific Coast = 60.2%; East = 16.4%; Total USA = 53.0%.

  • Source: Cancer registries in the Centers for Disease Control and Prevention's NPCR and/or the SEER program.

  • Abbreviation: W, non-Hispanic white.

  • aAI/AN race is reported by NPCR and SEER registries or through linkage with the IHS patient registration database. Includes only AI/AN of non-Hispanic origin.

  • bRank based on rates. AI/AN (white).

  • cRates are per 100,000 persons and are age-adjusted to the 2000 U.S. standard population (19 age groups - Census P25-1130).

  • dRRs are AI/AN versus white and are calculated in SEER*Stat prior to rounding of rates and may not equal RR calculated from rates presented in the table.

  • eIndicates RR is statistically significant (P < 0.05).