Table 1.

Comparison of DEPs identified in SEs of the OSCC-LNM group versus the HC group

NumberAccession numberAbbreviationFull nameMolecular weight (kDa)Sequence lengthQ valueaScorebOSCC-LNM/HCP valueExpression
1sp|P04275|VWFvon Willebrand factor309.2628130157.033.43264790.005
2tr|D3DP13|FGBFibrinogen beta chain, isoform CRA_e39.7363440100.23.16980380.008
3tr|B4E1I8|LRG1cDNA FLJ54228, highly similar to leucine-rich alpha-2-glycoprotein36.494330056.2392.84208430.029
4tr|Q6LAM1|CFIHeavy chain of factor I (fragment)35.883321031.8912.40307730.002
5tr|A2J1M2|ENSG00000223931Rheumatoid factor RF-IP9 (fragment)10.54998030.4412.20350860.028
6sp|P02671|FGAFibrinogen alpha chain94.972866088.9172.05092670.006
7tr|A0A125QYY9|ENSG00000223931IBM-B2 heavy-chain variable region (fragment)13.569123098.8951.89358520.003
8tr|A0A0F7SYK7|ENSG00000223931IGHV1-46 protein (fragment)10.17391015.4221.82748230.027
9tr|A0A024RAA7|C1QCComplement component 1, q subcomponent, C chain, isoform CRA_a25.773245094.9341.81698170.003
10tr|V9GYE7|CFHR2Complement factor H-related protein 228.912254024.4881.64605150.002
11tr|A8K2T4|C7cDNA FLJ78207, highly similar to human complement protein component C7 mRNA93.4068430323.311.60753090.040
12sp|Q06033|ITIH3Inter-alpha-trypsin inhibitor heavy-chain H399.848890082.3341.59613850.019
13tr|Q6N091|ENSG00000223931Uncharacterized protein DKFZp686C02220 (fragment)54.159500063.2671.54606530.030
14tr|A0A0 × 9UWK7|ENSG00000223931MS-D4 heavy-chain variable region (fragment)13.525122076.3211.54185790.035
15tr|A8K008|ENSG00000223931Uncharacterized protein51.596472062.7431.50191360.016
16sp|P10909|CLUClusterin52.4944490286.730.66526140.008
17tr|H0YAC1|KLKB1Plasma kallikrein (fragment)76.7736860148.390.65268570.005
18tr|Q5VY30|RBP4Retinol-binding protein 4, plasma, isoform CRA_b22.974199094.7940.6308160.029
19tr|B4E1B2|TFcDNA FLJ53691, highly similar to serotransferrin74.8316780323.310.63043940.039
20sp|P05546|SERPIND1Heparin cofactor 257.074990130.10.62681140.004
21tr|Q53FV4|LUMLumican variant (fragment)38.413338021.2070.60331610.001
22sp|A2NJV5|IGKV3D-7Immunoglobulin kappa variable 2-2913.085120023.7780.55285630.006
23sp|P06727|APOA4Apolipoprotein A-IV45.3983960261.290.52934840.030
24tr|A0A024R3E3|APOA1Apolipoprotein A-I, isoform CRA_a30.7772670323.310.49760170.015
25tr|X6RLJ0|C1QAComplement C1q subcomponent subunit A (fragment)23.351220023.9230.49457110.005
26tr|E9KL36|TTRTransthyretin15.8871470239.060.44772750.009
27tr|V9GYM3|APOA2Apolipoprotein A-II14.914133054.7230.44008520.008
28tr|D9YZU5|HBBBeta-globin15.9981470126.290.37734190.010
29tr|Q53H26|TFTransferrin variant (fragment)77.079698081.5530.34124720.021
30tr|A0A024R0T9|APOC2Apolipoprotein C-II isoform 111.284101030.1620.22077950.008
31tr|A0A0G2JRQ6|IGKV3D-7Uncharacterized protein (fragment)12.7481170.0030311.523Only detected in OSCC-LNM
32tr|A0A193CHR0|ENSG0000022393110E8 heavy-chain variable region (fragment)14.429131018.246Only detected in OSCC-LNM
33tr|B2R6V9|F13A1cDNA, FLJ93141, highly similar to Homo sapiens coagulation factor XIII, A1 polypeptide (F13A1), mRNA83.24732017.861Only detected in OSCC-LNM
34sp|P02741|CRPC-reactive protein25.038224029.616Only detected in OSCC-LNM
35sp|P0DOX4|ENSG00000223931Immunoglobulin epsilon heavy chain60.322547035.141Only detected in OSCC-LNM
36sp|P10720|PF4V1Platelet factor 4 variant11.553104020.13Only detected in HC
37tr|Q96SB0|IGKV3D-7Anti-streptococcal/anti-myosin immunoglobulin lambda light-chain variable region (fragment)11.594108035.763Only detected in HC
  • aQ value, the probability that the protein is a false hit.

  • bScore, the sum of the scores of the individual peptides.