Table 4.

Serum levels of 25(OH)D and OSa among patients with esophageal adenocarcinoma, stratified by BMI (n = 469)

25(OH)D QuartilesbN deaths/patientsHRc95% Confidence limits
BMI (≥18.5 and <25)Q1 (highest)30/37REF
Q226/380.680.40–1.17
Q334/381.080.65–1.79
Q4 (lowest)33/360.740.44–1.25
BMI (≥25 and <30)Q1 (highest)45/56REF
Q237/510.980.62–1.54
Q337/500.830.53–1.29
Q4 (lowest)32/451.140.71–1.82
BMI (≥30)Q1 (highest)15/21REF
Q218/291.320.65–2.67
Q323/341.510.77–2.96
Q4 (lowest)25/341.220.63–2.36
  • aOS was calculated as time between date of blood draw and date of death or date last known to be alive.

  • bQuartiles of vitamin D were determined accounting for month of blood draw.

  • cModel estimates adjusted for the main effect of vitamin D, age, sex, smoking status, the main effect of BMI categories, year of diagnosis, chemotherapy, radiation, time-dependent surgery, and baseline hazard was stratified by tumor stage by lymph node status.