Geometric mean serum PSA concentration (ng/mL) and 95% CIs by quintile of fibrosis scores among men ages 40 years and older, NHANES 2001–2010
APRI | ||||||
---|---|---|---|---|---|---|
Q1 (<0.24) | Q2 (0.24–<0.29) | Q3 (0.29–<0.35) | Q4 (0.35–<0.44) | Q5 (≥0.44) | Per 1 unit increase in fibrosis score (Ptrend) | |
Model 1a | 1.03 (0.98–1.09) | 0.96 (0.91–1.02) | 0.94 (0.89–0.99) | 0.97 (0.93–1.01) | 0.89 (0.84–0.95) | −0.36 (<0.001) |
Model 2b | 1.04 (0.99–1.10) | 0.96 (0.91–1.02) | 0.93 (0.89–0.98) | 0.97 (0.93–1.01) | 0.89 (0.84–0.95) | −0.38 (<0.001) |
FIB4 | ||||||
Q1 (<0.79) | Q2 (0.79–<0.99) | Q3 (0.99–<1.23) | Q4 (1.23–<1.62) | Q5 (≥1.62) | Per 1 unit increase in fibrosis score (Ptrend) | |
Model 1 | 1.03 (0.97–1.08) | 0.96 (0.92–1.01) | 0.97 (0.91–1.03) | 0.94 (0.89–0.99) | 0.90 (0.84–0.96) | −0.09 (0.007) |
Model 2 | 1.04 (0.99–1.10) | 0.97 (0.93–1.02) | 0.97 (0.92–1.03) | 0.94 (0.89–0.99) | 0.88 (0.83–0.95) | −0.11 (0.001) |
NFS | ||||||
Q1 (<2.72) | Q2 (2.72–<1.98) | Q3 (1.98–<1.24) | Q4 (1.24–<0.37) | Q5 (≥0.37) | Per 1 unit increase in fibrosis score (Ptrend) | |
Model 1 | 1.05 (1.00–1.11) | 0.99 (0.94–1.04) | 1.01 (0.96–1.05) | 0.92 (0.86–0.98) | 0.84 (0.78–0.91) | −0.06 (<0.001) |
Model 2 | 1.02 (0.96–1.08) | 0.96 (0.92–1.01) | 1.00 (0.95–1.04) | 0.93 (0.87–0.99) | 0.89 (0.82–0.96) | −0.04 (0.017) |