Table 2.

Geometric mean serum PSA concentration (ng/mL) and 95% CIs by quintile of fibrosis scores among men ages 40 years and older, NHANES 2001–2010

APRI
Q1 (<0.24)Q2 (0.24–<0.29)Q3 (0.29–<0.35)Q4 (0.35–<0.44)Q5 (≥0.44)Per 1 unit increase in fibrosis score (Ptrend)
Model 1a1.03 (0.98–1.09)0.96 (0.91–1.02)0.94 (0.89–0.99)0.97 (0.93–1.01)0.89 (0.84–0.95)−0.36 (<0.001)
Model 2b1.04 (0.99–1.10)0.96 (0.91–1.02)0.93 (0.89–0.98)0.97 (0.93–1.01)0.89 (0.84–0.95)−0.38 (<0.001)
FIB4
Q1 (<0.79)Q2 (0.79–<0.99)Q3 (0.99–<1.23)Q4 (1.23–<1.62)Q5 (≥1.62)Per 1 unit increase in fibrosis score (Ptrend)
Model 11.03 (0.97–1.08)0.96 (0.92–1.01)0.97 (0.91–1.03)0.94 (0.89–0.99)0.90 (0.84–0.96)−0.09 (0.007)
Model 21.04 (0.99–1.10)0.97 (0.93–1.02)0.97 (0.92–1.03)0.94 (0.89–0.99)0.88 (0.83–0.95)−0.11 (0.001)
NFS
Q1 (<2.72)Q2 (2.72–<1.98)Q3 (1.98–<1.24)Q4 (1.24–<0.37)Q5 (≥0.37)Per 1 unit increase in fibrosis score (Ptrend)
Model 11.05 (1.00–1.11)0.99 (0.94–1.04)1.01 (0.96–1.05)0.92 (0.86–0.98)0.84 (0.78–0.91)−0.06 (<0.001)
Model 21.02 (0.96–1.08)0.96 (0.92–1.01)1.00 (0.95–1.04)0.93 (0.87–0.99)0.89 (0.82–0.96)−0.04 (0.017)
  • aModel 1 adjusted for age and race.

  • bModel 2 adjusted for the age, race, BMI category, diabetes status, alcohol drinking status, and smoking status.