Table 1.

Trends in patient and tumor features

Total (N = 145,670)2000–03 (N = 34,554)2004–07 (N = 37,188)2008–11 (N = 41,783)2012–2014 (N = 32,145)
n (%)n (%)n (%)n (%)n (%)Pa
Age<0.001
 20–44 years17,860 (12.3)4,503 (13)4,725 (12.7)4,999 (12)3,633 (11.3)
 45–54 years40,512 (27.8)9,534 (27.6)10,710 (28.8)11,767 (28.2)8,501 (26.4)
 55–69 years56,512 (38.8)12,510 (36.2)13,782 (37.1)16,554 (39.6)13,666 (42.5)
 ≥70 years30,786 (21.1)8,007 (23.2)7,971 (21.4)8,463 (20.3)6,345 (19.7)
Race<0.001
 White113,396 (77.8)28,125 (81.4)29,440 (79.2)32,084 (76.8)23,747 (73.9)
 Black15,712 (10.8)3,222 (9.3)3,897 (10.5)4,647 (11.1)3,946 (12.3)
 Other15,112 (10.4)2,978 (8.6)3,561 (9.5)4,609 (11.0)3,964 (12.0)
 Unknown1,450 (1.0)229 (0.7)290 (0.8)443 (1.1)488 (1.5)
ER status<0.001
 Positive83,168 (57.1)4,857 (14.1)21,276 (57.2)30,865 (73.9)26,170 (81.4)
 Negative14,592 (10.0)1,198 (3.5)4,521 (12.2)5,125 (12.3)3,748 (11.7)
 Unknown47,910 (32.9)28,499 (82.5)11,391 (30.6)5,793 (13.9)2,227 (6.9)
PR status<0.001
 Positive68,961 (47.3)3,909 (11.3)17,314 (46.6)25,676 (61.5)22,062 (68.6)
 Negative22,783 (15.6)1,731 (5)6,732 (18.1)8,212 (19.7)6,108 (19)
 Unknown53,926 (37.0)28,914 (83.7)13,142 (35.3)7,895 (18.9)3,975 (12.4)
Tumor grade<0.001
 Grade I17,359 (11.9)3,854 (11.2)4,282 (11.5)5,081 (12.2)4,142 (12.9)
 Grade II50,862 (34.9)10,301 (29.8)12,553 (33.8)15,450 (37)12,558 (39.1)
 Grade III/IV55,060 (37.8)11,848 (34.3)14,803 (39.8)16,177 (38.7)12,232 (38.1)
 Unknown22,389 (15.4)8,551 (24.7)5,550 (14.9)5,075 (12.1)3,213 (10)
Tumor size<0.001
 1–10 mm49,926 (34.3)9,865 (28.6)12,612 (33.9)15,305 (36.6)12,144 (37.8)
 11–30 mm37,351 (25.6)7,510 (21.8)9,027 (24.3)11,038 (26.4)9,776 (30.4)
 >30 mm13,162 (9.0)2,204 (6.4)3,055 (8.2)4,156 (9.9)3,747 (11.7)
 Unknown45,231 (31.1)14,891 (43.2)12,494 (33.6)11,284 (27)6,478 (20.2)