Table 3.

Case-only analysis of pathogenic variants in ILC for family history (FH) of breast cancer (BC)

Carriers FH of BC vs. no FH in first-degree relativeCarriers FH of BC vs. no FH in any relative
GeneOR (95% CI)POR (95% CI)P
BRCA22.36 (1.05–5.31)0.0432.25 (1.02–4.98)0.046
CHEK22.59 (1.02–6.60)0.0673.95 (1.42–11.01)0.008
PALB22.94 (0.83–10.45)0.0973.26 (0.84–12.65)0.105
CDH12.95 (0.49–17.73)0.2382.11 (0.35–12.65)0.415
BRCA1010.419
TP53