Table 1.

Characteristics of the study population (EPIC-Heidelberg, case–cohort sample)

Subcohort
CasesWomenMenTotal
N1901,2571,1292,386
Age at recruitment (years)a55.9 (36.3–65.4)48.4 (35.2–66.0)53.2 (40.3–65.4)51.1 (35.2–66.0)
Age at diagnosis (years)a63.8 (38.1–82.0)
Median follow-up time (years)a9.1 (0.1–18.1)15.6 (0.1–18.5)15.4 (0.3–18.3)15.6 (0.1–18.5)
Women (%)2810052.7
Thrombopoietin (pg/mL)323 (271–412)349 (291–414)331 (281–397)339 (286–407)
Thrombomodulin (ng/mL)2.9 (2.4–3.5)2.7 (2.3–3.2)3.1 (2.6–3.6)2.9 (2.4–3.4)
sP-Selectin (ng/mL)34.3 (27.7–41.6)25.7 (20.5–31.7)30.2 (24.0–37.5)27.6 (22.0–34.4)
Glycoprotein IIb/IIIa (ng/mL)400 (320–514)384 (314–493)382 (316–487)383 (315–490)
Fibrinogen (μg/mL)4,097 (3,734–4,577)3,787 (3,399–4,277)3,775 (3,394–4,266)3,781 (3,398–4,270)
BMI (kg/m2)26.3 (23.7–29.0)24.3 (21.9–27.7)26.4 (24.3–28.9)25.6 (22.9–28.4)
Height (cm)171 (165–176)164 (160–168)176 (172–180)169 (163–176)
CRP (mg/dl)2.0 (0.9–4.3)1.0 (0.5–2.5)1.0 (0.5–2.6)1.0 (0.5–2.5)
Aspirin use (%)12.12.86.24.4
Smoking status (%)
 Never smokers8.450.833.842.8
 Long-term quitters (≥10 y)13.218.028.122.8
 Short-term quitters (<10 y)11.19.812.110.9
 Light smokers (<15 cig/d)14.213.612.313.0
 Heavy smokers (≥15 cig/d)53.27.713.710.5
  • NOTE: Values are medians (p25, p75) or proportions.

  • aMedian (min, max).