Table 1.

Ancestral proportions of commonly used human cancer cell lines

Cell lineATCC catalog numberGenderAgeTissueDesignated race/ethnicityWANAEURPutative ancestry
PC3CRL-1435M62Prostate cancerWhite/EA0.3%0.4%99.3%EA
DU145HTB-81M69Prostate cancerWhite/EA0.4%0.5%99.1%EA
LNCaPCRL-1740M50Prostate cancerWhite/EA6.5%1.9%91.7%EA
RWPE1CRL-11609M54Prostate cancerWhite/EA2.2%1.7%96.1%EA
22Rv1CRL-2505MN/AProstate cancerN/A0.3%0.4%99.3%EA
E006AA-hTCRL-3277M50Prostate canceraBlack/AA1.3%7.4%91.3%EA
MDA-PCa-2bCRL-2422M63Prostate cancerBlack/AA86.5%3.0%10.6%AA
RC-77T/EN/AM63Prostate cancerBlack/AA88.9%0.4%10.7%AA
HeLaCCL-2F31Cervical cancerBlack/AA66.5%0.4%33.1%AA
MCF-10ACRL-10317F36Breast diseaseWhite/EA0.9%2.4%96.7%EA
MDA-MB-453HBT-131F48Breast cancerWhite/EA0.2%0.4%99.4%EA
HCC1500CRL-2329F32Breast cancerBlack/AA78.8%0.5%20.7%AA
HCC1806CRL-2335F60Breast cancerBlack/AA80.2%4.4%15.4%AA
MDA-MB-468HTB-132F51Breast cancerBlack/AA77.1%22.7%0.2%AA/HA
T-47DHTB-133F54Breast cancerN/A0.1%0.3%99.7%EA
  • Abbreviations: AA, African American; EA, European American; EUR, European; F, female; HA, Hispanic American; M, male; NA, Native American; N/A, not available; WA, West African.

  • aE006AA-hT is sold by the ATCC as a prostate cancer cell line; however, ATCC acknowledges that the STR profile of this cell line is an 86% match to the 786-O renal cell carcinoma cell line (44).