Table 3.

List of factors that were assessed in the HQ studies

Number of HQ studies:
FactorAssessed factorStatistical significant finding
Age at DCIS diagnosis64
Calcification21
Calgranulin status10
COX-2 status21
Cyclin D1 status10
DCIS architecture62
Detection method42
ER status30
Focality10
Grade, histologic71
HER2 status30
Ki67 status20
Lesion size70
Margin status40
Menopausal status22
Necrosis40
p16 status21
p21 status10
p53 status30
Periductal fibrosis11
Periductal lymphocytes10
PR status30
Psoriasin status10
Race and/or ethnicity21
Subtypes, intrinsic20
Year of DCIS diagnosis10