Table 2.

ASRsa of pediatric malignant brain and CNS cancers per million person-years and APC by subtype, age, sex, and race/ethnicity, 1998–2013

n (%)ASR (95% CI)APC (95% CI)
Gliomas
Total10,664 (100)13.05 (12.81–13.31)0.77 (0.29–1.26)
Age, years
 0–42,906 (27.3)14.80 (14.26–15.34)0.55 (−0.08–1.18)
 5–92,919 (27.4)14.55 (14.03–15.09)0.73 (−0.40–1.87)
 10–142,471 (23.2)11.84 (11.37–12.31)1.09 (0.30–1.89)
 15–192,368 (22.3)11.12 (10.67–11.57)0.75 (−0.31–1.83)
Sex
 Male5,638 (52.9)13.47 (13.12–13.82)0.57 (−0.08–1.23)
 Female5,026 (47.1)12.62 (12.27–12.97)1.00 (0.30–1.71)
Ethnicity/raceb
 Latino1,712 (16.1)9.94 (9.47–10.42)−0.44 (−1.70–0.84)
 White7,057 (66.2)14.94 (14.59–15.29)1.31 (0.64–1.98)
 Black1,251 (11.7)10.61 (10.03–11.21)0.94 (−0.15–2.03)
 Other473 (4.4)8.86 (8.08–9.70)1.08 (−0.68–2.87)
 Unknown171 (1.6)
Embryonal
 Total5,423 (100)6.67 (6.49–6.85)−0.88 (−1.33 to −0.43)
Age, years
 0–42,250 (41.5)11.45 (10.99–11.94)0.14 (−1.03–1.33)
 5–91,560 (28.8)7.78 (7.40–8.17)−1.11 (−2.08 to −0.12)
 10–14968 (17.8)4.64 (4.35–4.94)−2.13 (−3.80 to −0.42)
 15–19645 (11.9)3.03 (2.80–3.27)−1.98 (−4.02–0.10)
Sex
 Male3,218 (59.3)7.74 (7.47–8.01)−0.86 (−1.36 to −0.36)
 Female2,205 (40.7)5.55 (5.32–5.79)−0.88 (−1.96–0.21)
Ethnicity/raceb
 Latino1,104 (20.4)6.21 (5.85–6.59)−2.55 (−3.54 to −1.56)
 White3,402 (62.7)7.31 (7.07–7.56)−0.66 (−1.33–0.01)
 Black590 (10.9)5.03 (4.64–5.46)0.30 (−0.66–1.27)
 Other280 (5.2)5.24 (4.65–5.89)0.03 (−2.40–2.52)
 Unknown47 (0.9)
Ependymal
 Total1,881 (100)2.30 (2.20–2.41)0.63 (−0.89–2.16)
Age, years
 0–4839 (44.6)4.27 (3.99–4.57)0.97 (−1.18–3.18)
 5–9393 (20.9)1.96 (1.77–2.16)−0.15 (−2.51–2.27)
 10–14328 (17.4)1.57 (1.41–1.75)−0.26 (−3.05–2.61)
 15–19321 (17.1)1.51 (1.35–1.68)1.89 (−1.53–5.43)
Sex
 Male1,034 (55.0)2.47 (2.32–2.63)1.16 (−0.54–2.89)
 Female847 (45.0)2.13 (1.99–2.27)−0.01 (−1.78–1.79)
Ethnicity/raceb
 Latino399 (21.2)2.26 (2.04–2.49)1.32 (−1.09–3.79)
 White1,158 (61.6)2.47 (2.33–2.62)0.25 (−1.48–2.01)
 Black211 (11.2)1.80 (1.56–2.06)1.11 (−3.16–5.56)
 Other101 (5.4)1.88 (1.53–2.28)4.05 (−0.23–8.52)
 Unknown12 (0.6)
Other
 Total644 (100)0.79 (0.73–0.85)−2.79 (−5.01 to −0.51)
Age, years
 0–4312 (48.4)1.59 (1.42–1.77)−2.00 (−4.28–0.35)
 5–997 (15.1)0.48 (0.39–0.59)−4.07 (−8.45–0.53)
 10–14117 (18.2)0.56 (0.46–0.67)−1.65 (−5.65–2.52)
 15–19118 (18.3)0.55 (0.46–0.66)−4.50 (−9.01–0.23)
Sex
 Male352 (54.7)0.84 (0.75–0.93)−3.27 (−5.69 to −0.8)
 Female292 (45.3)0.73 (0.65–0.82)−2.16 (−5.07–0.84)
Ethnicity/raceb
 Latino115 (17.9)0.63 (0.52–0.76)−4.32 (−8.77–0.34)
 White401 (62.3)0.86 (0.78–0.95)−3.16 (−6.22–0.01)
 Black87 (13.5)0.74 (0.59–0.91)−1.65 (−5.61–2.48)
 Other30 (4.7)0.56 (0.38–0.79)
 Unknown11 (1.7)
  • aAge-standardized to the 2000 U.S. standard population by 5-year age groups and expressed per million person-years.

  • bRace/ethnicity categories are mutually exclusive. Unknown race/ethnicity cancers do not have incidence rates or trends given a lack of denominator (population size) estimate for this group.