Table 1.

Clinical characteristics of the HPFS and PHS stratified by lowest tristetraprolin quartile

TristetraprolinLow (n = 101)TristetraprolinHigh (n = 303)P value
Cohort, n (%)0.55
 HPFS66(26)188(74)
 PHS35(23)115(77)
Age at diagnosis, median (SD; range)67.9 (7.0; 47–81)65.0 (6.2; 49–79)0.003
Pathologic RP Gleason score, n (%)<0.001
 2–610 (18)47 (82)
 749 (20)192 (80)
 813 (30)30 (70)
 9–1029 (46)34 (54)
Clinical stage, n (%)0.001
 T1/T278 (22)272 (78)
 T37 (26)20 (74)
 T412 (60)8 (40)
Total PSA at diagnosis, ng/mL, n (%)0.11
 0–44 (10)37 (90)
 4–1037 (19)159 (81)
 10–2016 (25)47 (75)
 >2012 (29)29 (71)
 Not available32 (51)31 (49)
Case status (%)<0.001
 Lethal49 (43)64 (57)
 Indolent52 (18)239 (82)
  • Abbreviation: RP, radical prostatectomy.