Table 1.

Study population characteristics

CharacteristicSurvivors with thyroid SMN, n (%), n = 118Survivors without thyroid SMN, n (%), n = 5,206P
Female76 (64.4)2,663 (51.2)0.004
Type of first cancer
 Leukemia32 (27.1)1,662 (31.9)<0.001
 CNS15 (12.7)628 (12.1)
 Hodgkin lymphoma39 (33.1)685 (13.2)
 Non-Hodgkin lymphoma6 (5.1)431 (8.3)
 Wilms tumor5 (4.2)493 (9.5)
 Neuroblastoma4 (3.4)386 (7.4)
 Soft tissue sarcoma6 (5.1)469 (9.0)
 Bone cancer11 (9.3)452 (8.7)
Age at first cancer diagnosis
 <15 years96 (81.4)4,251 (81.7)0.934
 ≥15 years22 (18.6)955 (18.3)
Year of birth
 1970 or before71 (60.2)2,373 (45.6)0.002
 After 197047 (39.8)2,833 (54.4)
Chemotherapy – alkylator71 (62.2)2,495 (50.9)0.016
Radiation100 (87.0)3,216 (65.1)<0.001
Radiation to neck69 (60.5)1,074 (22.2)<0.001
Thyroid nodules91 (83.5)523 (10.4)<0.001