Table 2.

Test characteristics for immunodiffusion and EIA serology to diagnose histoplasmosis

Immunodiffusion (95% CI)IgG Antibody (95% CI)IgM Antibody (95% CI)IgG or IgM (95% CI)IgG + IgM (95% CI)
Sensitivity13 (6–23)41 (29–53)13 (6–23)42 (30–55)12 (5–22)
Specificity95 (88–99)87 (78–93)96 (90–99)83 (73–91)100 (96–100)
PPV69 (39–91)72 (55–85)75 (43–95)67 (52–81)100 (63–100)
NPV57 (48–65)64 (54–73)57 (49–66)63 (54–72)58 (49–66)
Positive test133912438