Table 2.

Patient demographic and clinical characteristics for younger (18–49 years) and older (50+ years) age at breast cancer diagnosis, California, 2005–2014

AllYounger (18–49)Older (50+)
Total number of patients160,082 (100.0%)38,509 (100.0%)121,573 (100.0%)
Age (y), mean (SD)60.1 (13.6)42.8 (5.3)65.6 (10.5)
Age category
 18–398,822 (5.5%)8,822 (22.9%)
 40–4926,687 (18.5%)29,687 (77.1%)
 50–5940,840 (25.5%)40,840 (33.6%)
 60–69 40,163 (25.1%)40,163 (33.0%)
 70–7925,849 (16.1%)25,849 (21.3%)
 80+14,721 (9.2%)14,721 (12.1%)
Race/ethnicity
 Non-Hispanic white97,459 (60.9%)18,275 (47.5%)79,184 (65.1%)
 Non-Hispanic black9,831 (6.1%)2,581 (6.7%)7,250 (6.0%)
 Hispanic29,856 (18.7%)10,502 (27.3%)19,354 (15.9%)
 Asian/Pacific Islander21,159 (13.2%)6,714 (17.4%)14,445 (11.9%)
 Other/unknown1,777 (1.1%)437 (1.1%)1,340 (1.1%)
Marital status
 Married90,433 (56.5%)24,717 (64.2%)65,716 (54.1%)
 Unmarried63,794 (39.9%)12,497 (32.5%)51,297 (42.2%)
 Unknown5,855 (3.7%)1,295 (3.4%)4,560 (3.8%)
Neighborhood (block group) state-wide SES quintile
 1st (lowest)19,283 (12.0%)5,041 (13.1%)14,242 (11.7%)
 2nd27,202 (17.0%)6,413 (16.7%)20,789 (17.1%)
 3rd32,684 (20.4%)7,497 (19.5%)25,187 (20.7%)
 4th38,182 (23.9%)9,109 (23.7%)29,073 (23.9%)
 5th (highest)42,731 (26.7%)10,449 (27.1%)32,282 (26.6%)
Insurance status
 Private only94,291 (58.9%)29,199 (75.8%)65,092 (53.5%)
 Any Medicaid/military/other public26,350 (16.5%)7,701 (20.0%)18,649 (15.3%)
 Medicare only or Medicare + private33,918 (21.2%)33,918 (27.9%)
 No insurance1,259 (0.8%)475 (1.2%)784 (0.6%)
 Unknown4,264 (2.7%)1,134 (2.9%)3,130 (2.6%)
NCICC
 No143,322 (89.5%)32,708 (84.9%)110,614 (91.0%)
 Yes16,760 (10.5%)5,801 (15.1%)10,959 (9.0%)
AJCC stage
 I80,530 (50.3%)15,002 (39.0%)65,528 (53.9%)
 II59,779 (37.3%)16,990 (44.1%)42,789 (35.2%)
 III19,773 (12.4%)6,517 (16.9%)13,256 (10.9%)
Tumor subtype
 HR+/HER2103,807 (64.8%)22,331 (58.0%)81,476 (67.0%)
 HR+/HER2+15,893 (9.9%)5,235 (13.6%)10,658 (8.8%)
 HR/HER2+7,332 (4.6%)2,138 (5.6%)5,194 (4.3%)
 Triple negative16,677 (10.4%)5,176 (13.4%)11,501 (9.5%)
 Unclassified16,373 (10.2%)3,629 (9.4%)12,744 (10.5%)
Lymph node involvement
 Negative109,069 (68.1%)22,478 (58.4%)86,591 (71.2%)
 Positive50,925 (31.8%)16,019 (41.6%)34,906 (28.7%)
 Unknown88 (0.1%)12 (0.0%)76 (0.1%)
Tumor size (cm)
 0.10 < tumor ≤ 0.5011,782 (7.4%)2,343 (6.1%)9,439 (7.8%)
 0.50 < tumor ≤ 1.0027,166 (17.0%)4,600 (11.9%)22,566 (18.6%)
 1.00 < tumor ≤ 2.0058,110 (36.3%)12,737 (33.1%)45,373 (37.3%)
 2.00 < tumor ≤ 5.0052,235 (32.6%)15,080 (39.2%)37,155 (30.6%)
 >5.0010,789 (6.7%)3,749 (9.7%)7,040 (5.8%)
Grade
 Grade I36,815 (23.0%)6,141 (15.9%)30,674 (25.2%)
 Grade II67,075 (41.9%)14,893 (38.7%)52,182 (42.9%)
 Grade III/IV50,885 (31.8%)16,167 (42.0%)34,718 (28.6%)
 Unknown5,307 (3.3%)1,308 (3.4%)3,999 (3.3%)
Histology
 Ductal126,506 (79.0%)32,068 (83.3%)94,438 (77.7%)
 Lobular25,753 (16.1%)4,805 (12.5%)20,948 (17.2%)
 Other7,823 (4.9%)1,636 (4.2%)6,187 (5.1%)
Guideline-concordant treatment
 Yes47,057 (29.4%)15,434 (40.1%)31,623 (26.0%)
 No8,184 (5.1%)2,306 (6.0%)5,878 (4.8%)
 Not applicable104,530 (65.3%)20,665 (53.7%)83,865 (69.0%)
 Unknown311 (0.2%)104 (0.3%)207 (0.2%)