Table 2.

Associations between meat mutagens and CRA by sex and site

MutagenNumber of studiesResults, OR (95% CI)Phet
PhIP
 Male31.11 (0.89–1.38)0.453
 Female31.18 (0.71–1.96)0.157
 Colon41.18 (1.04–1.33)0.317
 Rectum31.23 (0.86–1.76)0.086
MelQx
 Male31.20 (0.95–1.51)0.510
 Female31.58 (1.09–2.30)0.498
 Colon31.14 (0.99–1.31)0.293
 Rectum20.90 (0.65–1.26)0.174
DiMelQx
 Male21.09 (0.87–1.36)0.827
 Female21.09 (0.67–1.77)0.731
 Colon31.04 (0.91–1.19)0.229
 Rectum20.99 (0.74–1.34)0.177
BaP
 Male
 Female
 Colon21.06 (0.83–1.35)0.062
 Rectum21.27 (0.94–1.72)0.168
Mutagenicity index
 Male21.46 (0.87–2.47)0.241
 Female21.13 (0.43–2.92)0.096
 Colon31.12 (0.97–1.29)0.261
 Rectum21.18 (0.71–1.96)0.042