Table 1.

Participant characteristics in the NCI-Maryland NSCLC Case–Control Study

EAAA
Controls N = 1,004Cases N = 816PControls N = 630Cases N = 404P
Age (years) (mean, standard deviation)66 (8.6)66 (10.5)<0.000164 (8.5)64 (9.5)0.01
Gender (N, %)0.50<0.0001
 Males561 (55.9)444 (54.4)496 (78.7)221 (54.7)
 Females443 (44.0)372 (45.6)134 (21.3)183 (45.3)
BMI (kg/m2) (N, %)<0.0001<0.0001
 <18.56 (1.0)46 (5.6)1 (<1.0)159 (39.7)
 18.5–24.9314 (31.5)357 (43.8)112 (17.8)127 (31.7)
 25.0–30.0388 (38.9)274 (33.6)229 (36.4)84 (21.0)
 >30.0293 (29.5)138 (17.9)288 (45.7)31 (7.7)
Missing3100
Smoking (N, %)<0.0001<0.0001
 Never smoker473 (47.1)87 (10.7)260 (41.3)28 (6.9)
 Former Smoker: Quit more than 1 year before interview424 (42.2)386 (47.3)255 (40.5)146 (36.1)
 Current Smoker93 (9.3)209 (25.6)99 (15.7)163 (40.4)
 Former Smoker: Quit within 1 year before interview13 (1.3)133 (16.3)15 (2.4)67 (16.6)
 Former Smoker: Quit unknown amount of time before interview1110
Pack-years of smoking (median, IQR)3.3 (0–28.75)40.6 (21.7–63.1)<0.00016.4 (0–24.1)30.1 (14.6–47.0)<0.0001
Education (N, %)<0.0001<0.0001
 Less than 11th grade35 (3.5)132 (16.2)51 (8.1)130 (32.2)
 High school or GED (12th grade)179 (17.9)276 (33.8)135 (21.5)122 (30.2)
 Some college (includes AA degree)214 (21.3)166 (20.3)177 (28.2)92 (22.8)
 Technical school23 (2.3)29 (3.6)10 (1.6)5 (1.2)
 College279 (27.8)129 (15.8)134 (21.2)33 (8.2)
 Professional school (includes MS, PhD, MD, etc.)273 (27.2)84 (10.3)121 (19.2)22 (5.5)
 Missing1020
Family history of lung cancer (N, %)<0.0001<0.0001
 No636 (63.4)436 (53.4)445 (70.6)241 (59.7)
 Yes238 (23.7)297 (36.4)104 (16.5)100 (24.8)
 Missing130838163
Histology (N, %)Per
 Adenocarcinoma370 (46.3)185 (46.3)
 Squamous cell carcinoma204 (25.5)99 (24.8)
 NSCLCa88 (10.8)45 (11.3)
 Other61 (7.6)29 (7.3)
 Missing9346
  • aThis classification includes largely adenocarcinomas, squamous cell carcinomas, and large-cell carcinomas; however, the pathologic classification at the time of diagnosis was NSCLC.

  • Percentages may not add up to 100% due to missing observations.