Table 3.

Antibody positivity to SGG proteins and colorectal cancer risk, overall and by time between blood draw and diagnosis (follow-up)

Overall<10 years follow-up≥10 years follow-up
ControlsCasesControlsCasesControlsCases
n = 4,063n = 4,063n = 2,766n = 2,766n = 1,296n = 1,296
SGG proteinn pos (%)n pos (%)ORa (95% CI)Pn pos (%)n pos (%)ORa (95% CI)Pn pos (%)n pos (%)ORa (95% CI)P
Gallo0112A320 (8)308 (8)0.96 (0.81–1.13)0.610228 (8)219 (8)0.96 (0.78–1.17)0.64792 (7)89 (7)0.96 (0.71–1.31)0.815
Gallo0272292 (7)302 (7)1.04 (0.88–1.23)0.671215 (8)237 (9)1.11 (0.92–1.35)0.28077 (6)65 (5)0.84 (0.60–1.17)0.311
Gallo0577246 (6)256 (6)1.05 (0.87–1.26)0.636175 (6)198 (7)1.15 (0.93–1.43)0.20771 (5)59 (4)0.80 (0.55–1.15)0.226
Gallo0748394 (10)372 (9)0.94 (0.81–1.09)0.402271 (10)263 (10)0.97 (0.81–1.16)0.717123 (9)109 (8)0.87 (0.66–1.15)0.325
Gallo1570266 (7)259 (6)0.97 (0.81–1.16)0.748183 (7)191 (7)1.05 (0.85–1.30)0.66383 (6)68 (5)0.80 (0.57–1.12)0.201
Gallo1675352 (9)351 (9)1.00 (0.85–1.17)0.968233 (8)257 (9)1.12 (0.93–1.35)0.250119 (9)94 (7)0.76 (0.57–1.02)0.067
Gallo2018287 (7)264 (7)0.91 (0.76–1.09)0.298226 (8)212 (8)0.93 (0.76–1.14)0.47652 (4)61 (5)0.84 (0.57–1.24)0.371
Gallo2178163 (4)197 (5)1.23 (0.99–1.52)0.063117 (4)160 (6)1.40 (1.09–1.79)0.00836 (4)37 (3)0.79 (0.50–1.24)0.300
Gallo2179209 (5)213 (5)1.02 (0.84–1.24)0.840149 (5)158 (6)1.07 (0.84–1.35)0.59360 (5)55 (4)0.91 (0.63–1.33)0.632
  • aConditional logistic regression model, controls are matched to cases by age, sex, and race/ethnicity; significant associations are marked in bold font (P < 0.05); and Pos = antibody positive.