Table 4.

Antibody positivity to Gallo2178 and colorectal cancer risk by p53 auto-antibody positivity and time between blood draw and diagnosis

NN (%) Gallo2178 pos
Follow-up timep53 autoantibodyControls/casesControlsCasesORa (95% CI)Pinteractiona
OverallNeg3865/3797156 (4)174 (5)1.15 (0.92–1.43)
Pos198/2667 (4)23 (9)2.74 (1.09–6.87)0.073
<10 yearsNeg2614/2540110 (4)139 (5)1.33 (1.02–1.72)
Pos152/2267 (5)21 (9)2.37 (0.92–6.09)0.315
≥10 yearsNeg1250/125646 (4)35 (3)0.74 (0.47–1.16)
Pos46/400 (0)2 (5)
  • Abbreviations: Neg, negative; Pos, positive.

  • aUnconditional logistic regression model with adjustment for study, sex, race, and age; significant associations (P < 0.05) are marked in bold font.