Table 2.

Risk factors for antibody positivity to SGG protein Gallo2178 among controls in the cohort consortium

VariableGallo2178 neg (n = 3900)Gallo2178 pos (n = 163)Pa
Study, n (%)
 CLUE484 (12)7 (4)
 CPS-II352 (9)9 (6)
 HPFS143 (4)8 (5)
 MEC701 (18)54 (33)
 NHS271 (7)17 (10)
 NYUWHS268 (7)18 (11)
 PHS174 (4)6 (4)
 PLCO607 (16)13 (8)
 SCCS116 (3)10 (6)
 WHI784 (20)21 (13)<0.0001
Age at blood draw (years)
 Median (range)64 (18–88)64 (31–84)0.399
Sex, n (%)
 Female2,447 (63)109 (67)
 Male1,453 (37)54 (33)0.285
Race/Ethnicity, n (%)
 White2,976 (76)91 (56)
 African American370 (9)29 (18)
 Asian American293 (8)14 (9)
 Latino189 (5)22 (13)
 Other/unknown/multiracial72 (2)7 (4)<0.0001
Education, n (%)
 Less than HS442 (11)26 (16)
 Completed HS or GED793 (20)30 (18)
 Post HS training other than college178 (5)5 (3)
 Some college814 (21)31 (19)
 College graduate722 (19)34 (21)
 Graduate school913 (23)33 (20)0.370
 Missing38 (1)4 (2)
BMIb (kg/m2), n (%)
 <302,670 (68)111 (68)
 > = 30)704 (18)44 (27)0.025
 Missing526 (13)8 (5)
Smoking, n (%)
 Never1,765 (45)88 (54)
 Ever2,096 (54)72 (44)0.021
 Missing39 (1)3 (2)
Family history of CRCc, n (%)
 No2,532 (65)106 (65)
 Yes391 (10)17 (10)0.887
 Missing977 (25)40 (25)
  • Abbreviations: CRC, colorectal cancer; GED, General Educational Development Test; HS, high school.

  • aχ2 test for categorical variables; t test for continuous variables (age); P values below 0.05 are considered statistically significant and are marked in bold font.

  • bAll studies except CLUE (variable not available).

  • cAll studies except NYUWHS, CLUE (variable not available), SCCS (<75% of variable information available).