Table 1.

Baseline characteristics of the cohorts participating in this study

VariableTotal (N = 8,126)Controls (n = 4,063)Cases (n = 4,063)
Study, n (%)
 CLUE982 (12)491 (12)491 (12)
 CPS-II722 (9)361 (9)361 (9)
 HPFS302 (4)151 (4)151 (4)
 MEC1,510 (19)755 (19)755 (19)
 NHS576 (7)288 (7)288 (7)
 NYUWHS572 (7)286 (7)286 (7)
 PHS360 (4)180 (4)180 (4)
 PLCO1,240 (15)620 (15)620 (15)
 SCCS252 (3)126 (3)126 (3)
 WHI1,610 (20)805 (20)805 (20)
Age at blood draw (years)
 Median (range)64 (18–89)64 (18–88)64 (18–89)
Sex, n (%)
 Female5,112 (63)2,556 (63)2,556 (63)
 Male3,014 (37)1,507 (37)1,507 (37)
Race/ethnicity, n (%)
 White6,134 (75)3,067 (75)3,067 (75)
 African American798 (10)399 (10)399 (10)
 Asian American614 (8)307 (8)307 (8)
 Latino422 (5)211 (5)211 (5)
 Other/unknown/multiracial158 (2)79 (2)79 (2)
Education, n (%)
 Less than HS972 (12)468 (12)504 (12)
 Completed HS or GED1,668 (21)823 (20)845 (21)
 Post HS training other than college362 (4)183 (5)179 (4)
 Some college1,672 (21)845 (21)827 (20)
 College graduate1,483 (18)756 (19)727 (18)
 Graduate school1,861 (23)946 (23)915 (23)
 Missing108 (1)42 (1)66 (2)
BMIa (kg/m2), n (%)
 <305,360 (66)2,781 (69)2,579 (64)
 ≥301,691 (21)748 (18)943 (23)
 Missing1,075 (13)534 (13)541 (13)
Smoking, n (%)
 Never3,628 (45)1,853 (46)1,775 (44)
 Ever4,409 (54)2,168 (53)2,241 (55)
 Missing89 (1)42 (1)47 (1)
Family history of CRCb, n (%)
 No5,167 (64)2,638 (65)2,529 (62)
 Yes907 (11)408 (10)499 (12)
 Missing2,052 (25)1,017 (25)1,035 (26)
  • Abbreviations: CRC, colorectal cancer; GED, General Educational Development Test; HS, high school.

  • aAll studies except CLUE (variable not available).

  • bAll studies except NYUWHS, CLUE (variable not available), and SCCS (<75% of variable information available).