Age-adjusted characteristics of the study population at baseline (1980 for the NHS and 1986 for the HPFS) according to quartiles of energy-adjusted dietary acrylamide intake
| Baseline dietary acrylamide intake quartile (μg/day) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Men (HPFS) | Women (NHS) | ||||||||
| Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 | Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 | ||
| Range: | ≤14.64 | 14.65–20.16 | 20.17–27.46 | ≥27.47 | ≤10.19 | 10.20–15.05 | 15.06–20.80 | ≥20.81 | |
| Characteristic | Median: | 11.06 | 17.42 | 23.23 | 35.11 | 7.12 | 12.65 | 17.63 | 25.80 |
| Number | 12,484 | 12,027 | 11,774 | 11,512 | 22,593 | 22,147 | 22,041 | 21,986 | |
| Mean age, years (SD)a | 57.1 (9.7) | 55.2 (9.7) | 53.8 (9.5) | 51.5 (9.2) | 48.3 (7.1) | 47.2 (7.2) | 46.4 (7.1) | 45.1 (6.9) | |
| Mean BMI, kg/m2 (SD) | 25.4 (3.5) | 25.5 (3.3) | 25.5 (3.2) | 25.7 (3.4) | 24.6 (4.7) | 24.4 (4.6) | 24.3 (4.4) | 24.3 (4.4) | |
| Diagnosis of hypertension | 24.4% | 21.8% | 20.8% | 20.8% | 19.7% | 17.0% | 14.8% | 13.4% | |
| Diabetes | 3.1% | 3.1% | 3.3% | 3.1% | 3.1% | 2.3% | 2.1% | 1.7% | |
| Smoking status | |||||||||
| Never | 51.9% | 48.7% | 44.6% | 41.7% | 49.1% | 47.2% | 42.6% | 35.6% | |
| Past, quit >10 years before baseline | 29.0% | 30.2% | 31.7% | 30.5% | 17.0% | 17.1% | 16.3% | 13.8% | |
| Past, quit ≤10 years before baseline | 11.2% | 12.0% | 13.7% | 14.7% | 11.7% | 10.9% | 11.5% | 11.1% | |
| Current | 7.9% | 9.1% | 10.1% | 13.2% | 22.2% | 24.8% | 29.6% | 39.5% | |
| Mean pack-years of smoking (SD)b | 23.9 (19.0) | 24.9 (19.0) | 25.5 (19.2) | 27.9 (20.1) | 19.0 (16.5) | 19.2 (16.4) | 20.5 (16.6) | 23.0 (17.0) | |
| Nulliparous | — | — | — | — | 6.3% | 5.9% | 5.5% | 5.7% | |
| Mean parity, number of children (SD)c | — | — | — | — | 3.1 (1.5) | 3.2 (1.5) | 3.2 (1.5) | 3.2 (1.5) | |
| Mean (SD) nutrient & food intakes | |||||||||
| Total calories, kcal/day | 1,997 (641) | 2,061 (615) | 1,931 (569) | 1,943 (640) | 1,569 (509) | 1,615 (504) | 1,576 (473) | 1,499 (513) | |
| Alcohol, g/day | 11.8 (17.2) | 12.1 (16.0) | 11.1 (14.2) | 10.0 (13.6) | 6.5 (11.4) | 6.6 (11.0) | 6.4 (10.1) | 5.7 (9.3) | |
| Breads, servings/dayd | 1.6 (1.3) | 2.0 (1.5) | 2.1 (1.6) | 2.1 (1.6) | 1.3 (1.0) | 1.5 (1.1) | 1.7 (1.2) | 1.7 (1.3) | |
| Baked goods, servings/weeke | 4.9 (6.6) | 6.4 (7.8) | 6.3 (7.5) | 6.4 (7.5) | 2.5 (3.2) | 3.8 (4.8) | 4.6 (6.1) | 5.5 (7.4) | |
| Cereal, servings/week | 2.1 (2.5) | 2.7 (2.8) | 3.1 (3.1) | 3.4 (4.6) | 1.7 (2.4) | 2.1 (2.6) | 2.1 (2.8) | 2.1 (3.2) | |
| Potatoes, servings/weekf | 2.7 (2.4) | 3.4 (2.4) | 3.8 (2.5) | 5.5 (3.6) | 2.3 (2.2) | 3.0 (2.4) | 3.4 (2.5) | 4.8 (3.8) | |
| Coffee, cups/dayg | 1.0 (1.2) | 1.7 (1.5) | 2.3 (1.8) | 2.8 (2.1) | 0.8 (1.0) | 1.8 (1.6) | 2.7 (1.8) | 3.6 (1.9) | |
NOTE: Percentages may not add up as expected due to rounding.
Abbreviation: BMI, body mass index.
↵aNot adjusted for age.
↵bAmong 24,396 male ever smokers and 49,822 female ever smokers.
↵cAmong 82,158 parous women.
↵dBreads include white bread, rye bread, other dark bread, English muffins/bagels/rolls, muffins/biscuits, pancakes/waffles, crackers, pizza, tortillas, pretzels, breakfast bars, energy bars, and high-protein bars.
↵eBaked goods include cookies, cake, pie, brownies, doughnuts, and sweet rolls/coffee cake/other pastries.
↵fPotatoes include baked/boiled/mashed potatoes, French fries, and potato chips.
↵gCoffee includes regular, decaffeinated, and dairy coffee drinks.