Table 3.

Subgroup analysis of severe BMI loss according to preoperative BMI levels

Overall survivalCancer-specific survival
No. at riskNo. of eventsMultivariable adjusted HR (95% CI)aNo. of eventsMultivariable adjusted HR (95% CI)a
Patients with preoperative BMI < 23.0
 BMI lossb ≤4.56981291 [Reference]671 [Reference]
 BMI loss >4.524132.86 (1.49–5.49)113.98 (1.86–8.51)
Patients with preoperative BMI ≥ 23.0
 BMI loss ≤4.5959971 [Reference]521 [Reference]
 BMI loss >4.5164382.01 (1.31–3.07)241.80 (1.02–3.19)
  • aCox regression models adjusted for age at diagnosis in years, sex (male [reference], female), ASAs classification (I [reference], II, or ≥III), smoking status (never [reference], past, or current), T-stage (1 [reference], 2, 3, or 4), N-stage (0 [reference], 1, 2, or 3), venous invasion (no [reference], yes), perineural invasion (no [reference], yes), histology (differentiated [reference], undifferentiated, or mixed), chemotherapy (no [reference], yes), and extent of gastric resection (distal gastrectomy [reference], total gastrectomy, proximal gastrectomy, or pylorus-preserving gastrectomy).

  • bBMI loss was calculated as preoperative BMI minus postoperative BMI.