Table 2.

Association of cSCC risk and mtDNA haplogroups in GERA non-Hispanic white subjects overall and stratified by sex

AllMenWomen
HaplogroupCase/control %OR (95% CI)PCase/control %OR (95% CI)PCase/control %ORP
A<1%0.58 (0.31–1.07)0.08<1%0.73 (0.35–1.52)0.40<1%0.36 (0.11–1.17)0.09
B<1%0.58 (0.26–1.28)0.18<1%0.80 (0.31–2.09)0.65<1%0.17 (0.02–1.25)0.08
C<1%0.78 (0.39–1.58)0.49<1%0.57 (0.20–1.64)0.30<1%1.10 (0.42–2.87)0.84
D<1%1.27 (0.61–2.62)0.53<1%1.82 (0.76–4.35)0.18<1%0.64 (0.15–2.74)0.55
HV<1%0.88 (0.63–1.23)0.44<1%0.87 (0.55–1.38)0.55<1%0.88 (0.54–1.43)0.59
I2.81/2.611.03 (0.87–1.22)0.712.88/2.561.15 (0.91–1.45)0.242.66/2.640.91 (0.71–1.17)0.46
J10.57/9.611.10 (1.00–1.21)0.05110.70/9.571.12 (0.98–1.28)0.1010.43/9.621.08 (0.94–1.25)0.28
JT<1%2.10 (0.49–8.99)0.32<1%4.41 (0.22–88.79)0.33<1%1.64 (0.30–9.07)0.57
K9.50/9.591.01 (0.91–1.11)0.929.34/9.931.01 (0.87–1.16)0.959.66/9.361.00 (0.86–1.16)0.99
L<1%0.81 (0.49–1.35)0.42<1%0.72 (0.35–1.47)0.36<1%0.92 (0.45–1.86)0.81
M<1%0.69 (0.40–1.20)0.19<1%0.80 (0.38–1.66)0.54<1%0.59 (0.25–1.36)0.21
N18.55/18.171.02 (0.94–1.11)0.5618.42/18.111.05 (0.94–1.18)0.3718.72/18.221.00 (0.89–1.12)0.93
P<1%1.74 (0.46–6.61)0.42<1%3.39 (0.52–22.15)0.20<1%0.91 (0.11–7.59)0.93
R4.57/5.010.95 (0.83–1.08)0.424.68/4.970.98 (0.82–1.18)0.824.43/5.030.91 (0.751.10)0.33
T10.09/10.350.96 (0.87–1.06)0.4410.07/10.320.97 (0.84–1.11)0.6310.11/10.380.96 (0.83–1.10)0.53
U14.18/14.640.95 (0.87–1.03)0.2014.40/14.800.96 (0.85–1.08)0.4713.93/14.530.94 (0.82–1.06)0.31
V<1%0.90 (0.47–1.72)0.74<1%0.96 (0.39–2.34)0.92<1%0.85 (0.33–2.19)0.74
W1.78/1.791.00 (0.81–1.22)0.961.90/1.861.14 (0.87–1.50)0.351.61/1.740.89 (0.65–1.21)0.46
X1.44/1.531.00 (0.80–1.25)0.991.49/1.521.09 (0.80–1.48)0.591.38/1.540.93 (0.66–1.29)0.64