Table 2.

Cox model assessing factors associated with breast cancer–specific death (SEER-18 excluding Alaska, 2010–2013)a

CovariatesHR95% CIP value
Clinical characteristics<0.0001
 Breast subtypes
  HR+/HER2Ref.
  HR+/HER2+0.77(0.73, 0.83)
  HR/HER2+1.24(1.16, 1.34)
  Triple-negative2.52(2.40, 2.65)
 AJCC 7th stage<0.0001
  IRef.
  II3.62(3.34, 3.91)
  III11.67(10.69, 12.73)
  IV32.70(29.98, 35.67)
 Bloom–Richardson grade<0.0001
  Low gradeRef.
  Medium grade1.30(1.20, 1.41)
  High grade2.12(1.97, 2.29)
 Nodal status>0.05
  NegativeRef.
  Positive0.99(0.94, 1.03)
 Surgery<0.0001
  Received surgeryRef.
  Did not receive surgery2.91(2.78, 3.04)
Demographic characteristics
 Age at diagnosis<0.0001
  <50Ref.
  50–641.26(1.20, 1.32)
  65–741.61(1.52, 1.70)
  75+3.07(2.90, 3.24)
 Race/ethnicity<0.0001
  Non-Hispanic whiteRef.
  Non-Hispanic black1.12(1.06, 1.18)
  Non-Hispanic API0.81(0.75, 0.88)
  Hispanic0.95(0.89, 1.01)
 Poverty 2010 (county level)<0.0001
  High SESRef.
  Medium SES1.15(1.07, 1.22)
  Low SES1.24(1.14, 1.35)
 Urban 2010 (county level)>0.05
  Less urban (<50%)Ref.
  More urban (≥50%)0.99(0.92, 1.06)
 Insurance status<0.0001
  UninsuredRef.
  Any Medicaid0.86(0.78, 0.94)
  Insured0.63(0.58, 0.69)
  Insured, NOS0.72(0.66, 0.80)
 Marital status<0.0001
  SingleRef.
  Otherb0.90(0.86, 0.94)
  • aCases were diagnosed from 2000 to 2013 and followed through December 31, 2014. We controlled for registry in the model.

  • bOther marital group contained married, partnered, and separated.