Table 3.

Number of cases (assuming an equal number of controls) required to detect an OR with 80% power and a disease prevalence of 1% assuming 1, 2, or 3 oral samples per subject based on the ICC estimated from the OMNIgene ORAL samples with a P value threshold of 0.05

OR
Estimated ICC#Specimens per subject1.502.002.503.003.50
Relative abundance of phylum-level taxaActinobacteria0.4611431477261181144
21045348190132105
391630516711692
Bacteroidetes0.6211062354193134107
286028615710987
379326414410080
Firmicutes0.4411496498273190151
21077359196136109
393831217111994
Fusobacteria0.67198332717912499
282027314910483
37662551409777
Proteobacteria0.67198332717912499
282027314910483
37662551409777
Candidate division SR10.73190230016411491
27802601429979
37392461359374
Alpha diversityChao10.73190230016411491
27802601429979
37392461359374
PD whole tree0.4511463487267185148
21061353193134107
392630816911793
Observed species0.74189029616211390
27742581419878
37352451349374
Shannon index0.5611176392214149119
291730516711692
383127715110584
Beta diversityBray Curtis distance0.70194031317111995
279926614610180
37522501379576
Unweighted UniFrac distance0.6411029343187130104
284328115410785
37822601429979
Weighted UniFrac distance0.67198332717912499
282027314910483
37662551409777