Table 2.

Previously published EOC risk loci confirmed by the OncoArray meta-analysis at P < 5 × 10−8 (ref. 23)a,b

LocusLead SNPPhenotypeEffect alleleEAFOR (95% CI)cPRef.
1p34.3rs58722170SerousC0.221.10 (1.07–1.13)1.4E−0925
2q14.1rs752590MucinousG0.211.30 (1.21–1.39)2.2E−1253
2q31.1rs711830MucinousA0.321.27 (1.20–1.35)1.1E−1453
2q31.1rs6755777SerousT0.321.12 (1.09–1.15)2.7E−1528
3q25.31rs62274041HGSOCG0.051.57 (1.48–1.66)2.1E−5722
5p15.33rs10069690SerousT0.261.13 (1.09–1.17)1.5E−1237
5p15.33rs7705526S. borderlineA0.331.38 (1.29–1.48)5.5E−1937
8q21.13rs76837345HGSOCG0.071.20 (1.13–1.28)9.0E−1026
8q24.21rs1400482SerousG0.871.23 (1.19–1.28)7.4E−2628
9p22.2rs10962692HGSOCG0.801.36 (1.30–1.42)1.4E−4722
9q34.2rs8176685HGSOCG0.191.15 (1.10–1.19)5.2E−1225
10p12.31rs144962376SerousTCCCT0.311.10 (1.06–1.13)6.6E−0926
17q12rs7405776SerousG0.411.10 (1.07–1.14)1.9E−1035
17q12rs11651755Clear cellC0.490.79 (0.73–0.86)6.8E−0935
17q21.31rs7207826SerousC0.271.14 (1.10–1.18)1.2E−1436
17q21.32rs1879586HGSOCG0.181.15 (1.10–1.19)2.5E−1226
19p13.11rs4808075HGSOCC0.301.20 (1.16–1.24)3.3E−2429
19q13.2rs688187MucinousA0.311.43 (1.33–1.53)1.2E−2253
In Han Chinese ancestry populations only
9q22.33rs1413299SerousC0.401.53 (1.25–1.86)1.9E−0824
10p11.21rs1192691SerousA0.360.81 (0.70–0.95)2.6E−0824
  • Abbreviations: EAF, effect allele frequency; ref., reference; S. borderline, serous borderline.

  • aIn European ancestry populations unless otherwise specified.

  • bAll risk loci listed had BFDP <10%.

  • cAll ORs, CIs, and P values from the OncoArray meta-analysis (ref. 23).