Table 2.

Previously published EOC risk loci confirmed by the OncoArray meta-analysis at P < 5 × 10⁻⁸ (ref. 23)^{^a^,^b}

Locus	Lead SNP	Phenotype	Effect allele	EAF	OR (95% CI)^c	P	Ref.
1p34.3	rs58722170	Serous	C	0.22	1.10 (1.07–1.13)	1.4E−09	25
2q14.1	rs752590	Mucinous	G	0.21	1.30 (1.21–1.39)	2.2E−12	53
2q31.1	rs711830	Mucinous	A	0.32	1.27 (1.20–1.35)	1.1E−14	53
2q31.1	rs6755777	Serous	T	0.32	1.12 (1.09–1.15)	2.7E−15	28
3q25.31	rs62274041	HGSOC	G	0.05	1.57 (1.48–1.66)	2.1E−57	22
5p15.33	rs10069690	Serous	T	0.26	1.13 (1.09–1.17)	1.5E−12	37
5p15.33	rs7705526	S. borderline	A	0.33	1.38 (1.29–1.48)	5.5E−19	37
8q21.13	rs76837345	HGSOC	G	0.07	1.20 (1.13–1.28)	9.0E−10	26
8q24.21	rs1400482	Serous	G	0.87	1.23 (1.19–1.28)	7.4E−26	28
9p22.2	rs10962692	HGSOC	G	0.80	1.36 (1.30–1.42)	1.4E−47	22
9q34.2	rs8176685	HGSOC	G	0.19	1.15 (1.10–1.19)	5.2E−12	25
10p12.31	rs144962376	Serous	TCCCT	0.31	1.10 (1.06–1.13)	6.6E−09	26
17q12	rs7405776	Serous	G	0.41	1.10 (1.07–1.14)	1.9E−10	35
17q12	rs11651755	Clear cell	C	0.49	0.79 (0.73–0.86)	6.8E−09	35
17q21.31	rs7207826	Serous	C	0.27	1.14 (1.10–1.18)	1.2E−14	36
17q21.32	rs1879586	HGSOC	G	0.18	1.15 (1.10–1.19)	2.5E−12	26
19p13.11	rs4808075	HGSOC	C	0.30	1.20 (1.16–1.24)	3.3E−24	29
19q13.2	rs688187	Mucinous	A	0.31	1.43 (1.33–1.53)	1.2E−22	53
In Han Chinese ancestry populations only
9q22.33	rs1413299	Serous	C	0.40	1.53 (1.25–1.86)	1.9E−08	24
10p11.21	rs1192691	Serous	A	0.36	0.81 (0.70–0.95)	2.6E−08	24

Abbreviations: EAF, effect allele frequency; ref., reference; S. borderline, serous borderline.
↵^aIn European ancestry populations unless otherwise specified.
↵^bAll risk loci listed had BFDP <10%.
↵^cAll ORs, CIs, and P values from the OncoArray meta-analysis (ref. 23).