Table 1.

Association of pancreatic cancer susceptibility variants with risk of breast cancer

Pancreatic cancerRootGAME-ON/DRIVE
SNPReference/effect alleleOR (95% CI)TypeaOR (95% CI)POR (95% CI)P
rs10919791G/A1.27 (1.18–1.33)Genotyped1.01 (0.86–1.18)0.9401.02 (0.97–1.06)0.465
rs11655237C/T1.26 (1.19–1.34)0.960.97 (0.87–1.09)0.6431.09 (1.02–1.16)0.007b
rs12413624A/T1.23 (1.16–1.31)0.990.99 (0.85–1.15)0.9021.03 (1.00–1.08)0.051
rs1486134T/G1.14 (1.09–1.19)Genotyped1.02 (0.90–1.16)0.7190.99 (0.95–1.03)0.538
rs1547374G/A1.27 (1.19–1.35)Genotyped1.01 (0.92–1.11)0.8331.01 (0.97–1.04)0.767
rs16986825C/T1.18 (1.12–1.25)Genotyped0.98 (0.76–1.26)0.8481.00 (0.96–1.05)0.997
rs17688601A/C1.14 (1.09–1.19)Genotyped0.93 (0.74–1.15)0.4791.01 (0.97–1.05)0.512
rs2736098T/C1.25 (1.18–1.32)0.951.09 (0.92–1.28)0.3301.05 (1.01–1.11)0.022b
rs31490A/G1.20 (1.14–1.27)Genotyped1.12 (1.02–1.23)0.020b0.99 (0.95–1.02)0.491
rs372883C/T1.27 (1.19–1.33)Genotyped1.00 (0.91–1.10)0.9881.00 (0.96–1.03)0.899
rs3790844A/G1.30 (1.19–1.41)Genotyped1.03 (0.89–1.20)0.7031.01 (0.97–1.05)0.675
rs401681C/T1.20 (1.13–1.28)1.000.89 (0.81–0.98)0.018b1.01 (0.98–1.05)0.416
rs505922T/C1.27 (1.19–1.35)1.001.04 (0.94–1.14)0.4580.96 (0.93–1.00)0.032b
rs5768709A/G1.25 (1.17–1.34)0.980.98 (0.89–1.09)0.7380.99 (0.95–1.03)0.624
rs687289G/A1.27 (1.20–1.35)Genotyped1.06 (0.96–1.16)0.2640.96 (0.93–0.99)0.021b
rs6971499C/T1.27 (1.19–1.35)Genotyped0.99 (0.87–1.14)0.9271.02 (0.96–1.08)0.537
rs7190458G/A1.46 (1.30–1.65)0.910.93 (0.83–1.04)0.1791.05 (0.97–1.15)0.225
rs9543325T/C1.24 (1.16–1.32)Genotyped1.05 (0.89–1.25)0.5290.99 (0.96–1.03)0.684
rs9554197C/T1.14 (1.10–1.19)Genotyped1.03 (0.91–1.17)0.6061.00 (0.97–1.03)0.986
rs9573163C/G1.26 (1.18–1.34)0.990.90 (0.79–1.04)0.1571.01 (0.97–1.04)0.741
rs9581943G/A1.15 (1.10–1.20)Genotyped1.03 (0.87–1.22)0.705
rs962856T/C1.12 (1.08–1.17)Genotyped1.09 (0.97–1.22)0.1641.00 (0.97–1.04)0.954
rs9854771A/G1.12 (1.08–1.18)Genotyped1.06 (0.95–1.18)0.2760.97 (0.93–1.01)0.107
  • aNumbers indicate the imputation scores.

  • bThe P values are significant at nominal level (<0.05), but turn out to be nonsignificant after multiple correction.