Table 1.

Line listing of included studies by cancer site

Site of cancerStudy authors, publication yearCountryScreening testStudy length yearsNumber of MSU examsStudy designa case detection reported
Breast cancerReuben, 2002 (37)USAMammogram (NOS)2129RCT
Rimer, 1992 (59)USAMammogram (NOS)RCT
Williams, 1989 (77)UKMammogram (NOS)316RCT
Tabar, 1981 (22)SwedenFilm mammogram2.334,187RCTa
Strax, 1973 (23)USAFilm mammogram, CBE520,211RCTa
Hughes, 2014 (13)AustraliaFilm mammogram9214,328Prospective cohorta
Mizuguchi, 2014 (53)USADigital, film mammogram1048,324Prospective cohorta
Horton, 1996 (66)UKFilm mammogram0.54,578Prospective cohort
Roen, 2013 (33)USADigital mammogram21,771Retrospective cohort
Del Turco, 2007 (18)ItalyDigital, film mammogram1.828,770Retrospective cohorta
Zappa, 2002 (76)ItalyFilm mammogram980,134Retrospective cohorta
Fayanju, 2014 (34)USAMammogram (NOS)57,334Cross-sectional
Fontenoy, 2013 (14)CanadaDigital, film mammogram842,279Cross-sectionala
Van Hal, 1999 (78)BelgiumMammogram (NOS)0.2Cross-sectional
Stark, 1997 (28)UKMammogram (NOS)Cross-sectional
Orton, 1991 (46)UKMammogram (NOS)11,408Cross-sectional
Séguret, 1995 (72)FranceFilm mammogram2.526,026Cross-sectionala
Roberson, 1994 (63)USACBE271Cross-sectional
Al Mulhim, 2015 (69)Saudi ArabiaDigital mammogram58,061Descriptive
Apffelstaedt, 2014 (31)South AfricaDigital mammogram1.52,712Descriptivea
Renck, 2014 (16)BrazilMammogram (NOS)9,919Descriptivea
Brooks, 2013 (42)USADigital mammogram, CBE24,543Descriptivea
Carkaci, 2013 (17)USADigital, film mammogram206,776Descriptivea
Haikel, 2013 (30)BrazilFilm mammogram210,521Descriptivea
Lee, 2013 (79)TaiwanMammogram (NOS)0.3Descriptive
Vyas, 2013 (44)USADigital mammogram21,161Descriptive
Bond, 2009 (41)UKMammogram (NOS)339,260Descriptive
Rodriguez-Cuevas, 2009 (71)MexicoFilm mammogram1.596,828Descriptivea
Copeland, 2008 (45)USAMammogram (NOS)13,336Descriptive
Peek, 2007 (43)USAMammogram (NOS)1.5Descriptive
Maheswaran, 2006 (39)UKMammogram (NOS)316,695Descriptive
Lane, 2003 (51)USAMammogram (NOS)141Descriptive
Tinkler, 2001 (80)UKMammogram (NOS)0.7Descriptive
Gordenne, 2000 (78)BelgiumMammogram (NOS)852,475Descriptivea
Frelix, 1999 (35)USAFilm mammogram, CBE1.11,935Descriptivea
Swaddiwudhipong, 1999 (81)ThailandCBE1Descriptivea
Kann, 1998 (82)USAFilm mammogram, CBE519,280Descriptivea
Schweitzer, 1998 (83)USAFilm mammogram310,859Descriptive
Falshaw, 1996 (32)UKMammogram (NOS)338Descriptive
Kohli, 1995 (40)UKMammogram (NOS)111,425Descriptive
Sutton, 1995 (65)UKMammogram (NOS)0.3306Descriptive
Van Oyen, 1994 (74)BelgiumMammogram (NOS)316,017Descriptivea
Garas, 1994 (73)GreeceFilm mammogram22,258Descriptivea
McCoy, 1992 (36)USAFilm mammogram4.316,354Descriptivea
Dershaw, 1992 (55)USAFilm mammogram322,540Descriptivea
Kessler, 1991 (56)USAFilm mammogram1.13,627Descriptive
Williams, 1990 (84)UKFilm mammogram46,409Descriptive
Rubin, 1990 (85)USAFilm mammogram0.52,099Descriptive
Haiart, 1990 (68)UKFilm mammogram0.56,080Descriptive
Kettlehake, 1988 (57)USAFilm mammogram0.95,000Descriptive
Hamilton, 2003 (62)UKMammogram (NOS)Qual. descriptive
Scammon, 1991 (38)USAMammogram (NOS)Qual. descriptive
Kennedy, 2009 (60)USAMammogram (NOS)2Case study
Nielsen, 1991 (86)USAMammogram (NOS), CBE∼8,000Case study
Kluhsman, 2009 (52)USAFilm mammogram184,606Descriptive
Cervical cancerFregnani, 2013 (27)BrazilPap, Pap-LBC0.612,048Cross-sectionala
Megevand, 1996 (15)South AfricaPap, VIA0.75,045Prospective cohorta
Lorenzi, 2016 (21)BrazilHPV testing, Pap-LBC0.83,068Descriptivea
Ferris, 2015 (26)PeruPap21,700Descriptive
Cheng, 2014 (87)TaiwanPap585Descriptive
Paengchit, 2014 (25)ThailandHPV testing, Pap-LBC0.32,000Descriptivea
Riza, 2000 (88)GreecePap919,961Descriptive
Swaddiwudhipong, 1999 (20)ThailandPap4Mixed-methods: Descriptivea
Thornton, 1989 (54)UKPap, CBE0.5568Descriptivea
Brindle, 1976 (49)UKPap0.11,526Descriptivea
Whitfield, 1972 (50)UKPap31,952Descriptivea
Logan, 2011 (61)IrelandPapCase study
ColonBruwer, 2013 (29)South AfricaColonoscopy2Case study
Multiple sitesSchnippel, 2015 (89)South AfricaBreast and cervical cancer: CBE, Pap and VIA11,756Cost-effectiveness
Mauad, 2009 (70)BrazilBreast and cervical cancer: Film mammogram, Pap17,192, 2,964Descriptivea
Alexy, 1998 (90)USABreast, Cervical: CBE, PapDescriptive
Craddock, 1975 (91)UKBreast, cervical: Mammogram (NOS), PapDescriptive
Seacome, 1971 (92)UKBreast, Cervical: CBE, Pap0.5Descriptive
Whitfield, 1970 (93)UKBreast, Cervical: CBE, Pap0.21,064Descriptive
Kumar, 2011 (24)IndiaBreast, cervical and oral: CBE, VIA/VILI, OVE0.3182Descriptive
Yoon, 2009 (64)KoreaBreast, cervical, gastric, liver, colon: MMG + CBE, Pap, upper GI series/endoscopy, serum alpha fetoprotein tests and abdominal ultrasonography, FOBT0.3Cross-sectional
Lynch, 1976 (94)USABreast, cervical, prostate, gastric, oral, lung, colon: Tests unspecified45,232 totalDescriptivea
Lynch, 1973 (67)USABreast, cervical, prostate, gastric, oral, lung, CRC, penile: Mammogram (NOS), CBE, Pap, DVI, OVE, indirect laryngoscopy, proctosigmoidoscopy1Descriptivea
  • Abbreviations: CBE, Clinical breast exam; DVI, Direct visual inspection; Pap, Papanicolau smear with conventional cytology; Pap-LBC, Papanicolau smear with liquid based cytology; NOS, not otherwise specified; OVE, oral visual examination; VILI, visual inspection with Lugol iodine.

  • aStudies report results for number of detected cases of cancer and/or test performance.