Table 2.

The association of waist circumference with prostate cancer risk among men in the CPS-II Nutrition Cohort

Waist circumference
Q1Q2Q3Q4Q5
58.4–<91.8 cm90.8–<95.3 cm95.3–<100.3 cm100.3–<106.7 cm≥106.7 cmPer 10 cm
All cases
 Number of cases1,1771,1211,1971,0061,2105,711
 Person-years100,24694,099111,70190,941112,023509,013
 RR (95% CI)a1.00 (ref)1.01 (0.93–1.09)0.91 (0.84–0.99)0.94 (0.87–1.03)0.93 (0.86–1.01)0.97 (0.95–1.00)
 RR (95% CI)b1.00 (ref)1.02 (0.94–1.11)0.93 (0.85–1.01)0.97 (0.88–1.07)0.98 (0.87–1.10)0.99 (0.95–1.04)
Low-grade cases
 Number of cases9749129887869484,608
 Person-years100,24694,099111,70190,941112,023509,013
 RR (95% CI)a1.00 (ref)0.99 (0.90–1.08)0.91 (0.83–1.00)0.89 (0.81–0.98)0.88 (0.80–0.96)0.95 (0.92–0.98)
 RR (95% CI)b1.00 (ref)1.00 (0.91–1.10)0.93 (0.84–1.02)0.92 (0.82–1.02)0.92 (0.81–1.05)0.97 (0.93–1.02)
High-grade cases
 Number of cases155148155154197809
 Person-years100,24694,099111,70190,941112,023509,013
 RR (95% CI)a1.00 (ref)1.00 (0.80–1.26)0.89 (0.71–1.11)1.08 (0.87–1.36)1.16 (0.94–1.44)1.06 (0.98–1.14)
 RR (95% CI)b1.00 (ref)1.00 (0.79–1.26)0.88 (0.69–1.12)1.07 (0.83–1.38)1.13 (0.84–1.53)1.04 (0.93–1.17)
Lethal cases
 Number of cases84817373105416
 Person-years118,721112,037131,946107,264131,925601,896
 RR (95% CI)a1.00 (ref)1.01 (0.74–1.38)0.74 (0.54–1.02)0.91 (0.66–1.25)1.14 (0.85–1.53)1.06 (0.96–1.17)
 RR (95% CI)b1.00 (ref)1.01 (0.74–1.39)0.74 (0.53–1.04)0.91 (0.64–1.31)1.14 (0.75–1.72)1.07 (0.91–1.26)
  • aAdjusted for age, race, family history of prostate cancer, history of PSA testing (time-dependent), history of diabetes (time-dependent), physical activity, energy intake, education, and alcohol intake.

  • bAdditionally adjusted for BMI.