Table 5.

Associations of rs2296972(HTR2A), rs33388 (NR3C1), and rs6277 (DRD2) with mRNA expression in the corresponding pathways in the Swedish Watchful Waiting Cohorta

mRNAsβP
In association with rs2296972 (HTR2A)
 GNAI2−0.1560.023
 GNAI10.2230.035
In association with rs33388 (NR3C1)
 SMAD4−0.2220.010
 MAPK14−0.1330.018
 SLC22A10.1610.028
 POU2F1−0.2010.030
 MMP130.0680.040
 NFKB10.1220.049
In association with rs6277 (DRD2)
 FOS0.3020.021
 SRC0.1510.032
  • aAll models were adjusted for age at diagnosis, calendar period at diagnosis, tumor stage, Gleason score, and lethal cancer. Only mRNAs associated with the index SNP (P < 0.05) were presented in the table.