Table 1.

Overview of cancers analyzed

Cancer typeCasesControlsEmbedded Image (SE) – observed scaleEmbedded Image (95% CI) – liability scale
Breast15,74818,0840.12 (0.02)0.14 (0.09–0.18)
Colorectal15,71618,1540.13 (0.02)0.11 (0.07–0.14)
Lung12,16016,8380.14 (0.03)0.13 (0.08–0.19)
Ovarian4,3699,1230.10 (0.04)0.07 (0.02–0.12)
Pancreatic5,1078,8450.07 (0.04)0.05 (0–0.10)
Prostate14,16012,7240.25 (0.03)0.27 (0.21–0.33)
  • NOTE: Number of subjects, observed heritability (standard error) and heritability (95% CI) on the liability scale explained by studied SNPs for each cancer. Cumulative risks used for calculating Embedded Image on the liability scale were obtained from SEER.