Table 2.

All-cause mortality after diagnosis and breast cancer risk factors in the WHI biospecimen cohort among women diagnosed with incident breast cancer, by hsCRP level (n = 1,114)

CRP < 1.5 mg/L1.5 ≤ CRP < 2.39 mg/L2.39 ≤ CRP < 4.45 mg/LCRP ≥ 4.45 mg/L
Variablen = 240n = 286n = 265n = 323Pa
%%%%
ER+ (14.6% missing)79.981.378.4770.44
PR+ (17.8% missing)57.865.551.457.10.18
Stage (2.7% missing)
 In situ22.614.921.217.20.35
 Localized58.363.754.458.9
 Regional18.319.92221.7
 Distant0.91.42.32.3
BMI group
 BMI < 2541.721.314.311.1<0.001
 25 ≤ BMI < 3035.840.23428.5
 30 ≤ BMI <3517.124.532.130.3
 BMI ≥ 355.41419.630
BMI (kg/m2), mean (SD)26.8 (5.34)29.3 (5.85)30.4 (5.04)31.9 (5.76)<0.001
Age at BC diagnosis mean (SD)71.2 (7.56)71.5 (7.94)71.3 (8.12)70.3 (7.41)0.09
  • Abbreviations: BC, breast cancer; PR+, progesterone receptor positive.

  • aTest of trend in simple linear regression with log(CRP).