Table 1.

Demographic characteristics of cHL cases and matched controls

CaseControl
Characteristics(n = 103) N (%)(n = 206) N (%)
Age (y)a
 18–2341 (39.8%)79 (38.4%)
 24–3030 (29.1%)63 (30.6%)
 >3032 (31.1%)64 (31.1%)
Age (y), median (IQR)25.9 (21.9–31.4)25.5 (22.0–31.1)
Sexa
 Male93 (90.3%)186 (90.3%)
 Female10 (9.7%)20 (9.7%)
Race/ethnicitya
 White, non-Hispanic77 (74.8%)153 (74.3%)
 Black, non-Hispanic12 (11.7%)24 (11.7%)
 Hispanic11 (10.7%)22 (10.7%)
 Other/unknown3 (2.9%)7 (3.4%)
Year of earliest serum collectiona
 1988–199151 (49.5%)102 (49.5%)
 1992–199422 (21.4%)45 (21.8%)
 1995–199930 (29.1%)59 (28.6%)
Years from earliest blood collection to diagnosis, median (IQR)2.8 (1.4–4.9)2.8 (1.2–4.9)
Number of serum samplesa
 139 (37.9%)78 (37.9%)
 255 (53.4%)110 (53.4%)
 46 (5.8%)12 (5.8%)
 53 (2.9)6 (2.9%)
Histologic subtype
 Nodular sclerosis67 (65.1%)
 Mixed cellularity13 (12.6%)
 Classical HL, not further classified23 (22.3%)
Tumor EBV status
 EBV negative76 (76.7%)
 EBV positive23 (23.2%)
 EBV indeterminate4 (3.9%)
  • Abbreviations: cHL, classical Hodgkin lymphoma; IQR, Interquartile range.

  • aControls were matched to cases on age at diagnosis of case, sex, race/ethnicity, serum collection date, and number of serum samples.