Table 1.

Summary of demographic information for families from three study cohorts

MDACC pediatric sarcomaISKS adult sarcomaNCI LFS
Among all familiesNumber of carriers > 0Number of carriers = 0Number of carriers > 0Number of carriers = 0Number of carriers > 0Number of carriers = 0Total
Number of families11 (6.0%)172 (94.0%)19 (3.3%)563 (96.7%)78 (76.5%)24 (23.5%)867
Number of individuals1,256 (49.2%)1,297 (50.8%)591 (3.5%)16,386 (96.5%)1,857 (69.4%)819 (30.6%)22,206
Average age at first diagnosis46.4 (SD = 23.9)26.2 (SD = 24.3)46.3 (SD = 21.8)54.7 (SD = 18.7)39.9 (SD = 22.1)52.5 (SD = 22.0)
Number of individuals with number of cancers = 1127 (10.1%)265 (20.4%)78 (13.2%)1,788 (10.9%)336 (18.1%)159 (19.4%)2,753
Number of individuals with number of cancers = 219 (1.5%)0 (0%)7 (1.2%)165 (1.0%)91 (4.9%)22 (2.7%)304
Number of individuals with number of cancers > 27 (0.6%)0 (0%)8 (1.4%)48 (0.3%)51 (2.7%)11 (1.3%)125
  • Abbreviation: SD, standard deviation.