Table 2.

Alcohol consumptiona in DNA MMR gene germline mutation carriers

WomenMenOverall
No colorectal cancerColorectal cancerTotalNo colorectal cancerColorectal cancerTotalNo colorectal cancerColorectal cancerTotal
N = 725 (67%)N = 352 (33%)N = 1,077N = 431 (51%)N = 417 (49%)N = 848N = 1,156 (60%)N = 769 (40%)N = 1,925
Average daily ethanol intake from any alcoholic beverage (g/day),
 Mean (SD)4.2 (9.6)3.9 (7.7)4.1 (9.1)15.9 (21.1)20.4 (25.9)18.1 (23.7)8.6 (16.0)12.9 (21.4)10.3 (18.5)
 Median (range)1.1 (0–176.8)0.6 (0–63.8)0.9 (0–176.8)9.2 (0–157.9)11.9 (0–172.0)9.9 (0–172.0)3.1 (0–176.8)3.5 (0–172.0)3.2 (0–176.8)
 Missing (%)80 (11.0)41 (11.6)121 (11.2)42 (9.7)47 (11.3)89 (10.5)122 (10.6)88 (11.4)210 (10.9)
Average daily ethanol intake from beer (g/day),
 Mean (SD)1.3 (4.1)1.2 (4.0)1.2 (4.0)10.9 (15.5)15.1 (24.1)13.0 (20.3)4.9 (11.1)8.7 (19.3)6.4 (15.0)
 Median (range)0 (0–43.9)0 (0–38)0 (0–44)5.3 (0–93.3)6.7 (0–168)6 (0–168)0 (0–93.3)0.7 (0–168)0 (0–168)
 Missing (%)44 (6.1)25 (7.1)69 (6.4)25 (5.8)29 (7.0)54 (6.4)69 (6.0)54 (7.0)123 (6.4)
Average daily ethanol intake from wine (g/day),
 Mean (SD)1.8 (4.4)1.4 (3.5)1.6 (4.1)2.2 (5.6)1.8 (4.3)2.0 (5.0)1.9 (4.9)1.6 (4.0)1.8 (4.5)
 Median (range)0 (0–71.2)0 (0–29.6)0 (0–71.2)0 (0–69.3)0 (0–30.1)0 (0–69.3)0 (0–71.2)0 (0–30.1)0 (0–71.2)
 Missing (%)40 (7.6)23 (6.5)63 (5.8)21 (4.9)18 (4.3)39 (4.6)61 (5.3)41 (5.3)102 (5.3)
Average daily ethanol intake from spirits (g/day),
 Mean (SD)1.1 (4.6)1.1 (2.8)1.1 (4.1)2.5 (6.1)2.9 (9.3)2.7 (7.8)1.6 (5.3)2.0 (7.2)1.8 (6.1)
 Median (range)0 (0–105.6)0 (0–22.1)0 (0–105.6)0 (0–50.8)0 (0–111.6)0 (0–111.6)0 (0–105.6)0 (0–111.6)0 (0–111.6)
 Missing (%)55 (5.5)27 (7.7)82 (7.6)31 (7.2)30 (7.2)61 (7.2)86 (7.4)57 (7.4)143 (7.4)
  • Abbreviation: g/day, grams per day.

  • aAt the time of colorectal cancer diagnosis or age of another cancer, or polypectomy, or interview for colorectal cancer–unaffected participants (whichever came first).