Table 1.

General baseline characteristics by sex for FACT participants with PTHM measures

All participants (N = 324)Males (n = 162)Females (n = 162)
CharacteristicMedian (IQR)Median (IQR)Median (IQR)Pa
Age, y39 (34–44)42 (36–46)37 (31–42)<0.01
BMI,b kg/m219.2 (17.7–21.3)18.7 (17.7–20.3)20.0 (17.9–22.5)<0.01
Blood arsenic, μg/L8.7 (6.0–12.4)9.5 (6.5–12.4)7.9 (5.3–12.4)0.04
bSe, μg/L134 (122–149)135 (123–151)132 (120–146)0.16
RBC folate,c nmol/L451 (363–603)434 (362–572)461 (364–607)0.34
Plasma folate, nmol/L12 (9–17)12 (8–16)13 (10–18)0.10
Plasma vitamin B12, pmol/L215 (153–319)217 (154–296)213 (153–338)0.49
Plasma choline, μmol/L11.0 (9.8–13.1)11.9 (10.4–13.3)10.7 (9.0–12.4)<0.01
Plasma betaine, μmol/L42.8 (33.9–52.0)47.0 (40.2–57.5)37.3 (28.9–44.9)<0.01
Plasma Hcys, μmol/L11.4 (8.8–15.5)14.2 (11.1–17.4)9.3 (7.4–12.0)<0.01
H3K36me2,d relative % of total H31.44 (1.26–1.72)1.45 (1.26–1.76)1.43 (1.26–1.70)0.66
H3K36me3,e relative % of total H31.61 (1.32–1.88)1.56 (1.26–1.84)1.63 (1.37–1.94)0.10
H3K79me2,f relative % of total H31.27 (1.03–1.76)1.26 (1.05–1.74)1.29 (1.01–1.85)0.96
Folate deficient,g %23.228.417.90.03
Vitamin B12 deficient,h %24.424.124.70.90
HHcys,i %40.762.419.1<0.01
Ever smoked cigarette, %28.856.21.2<0.01j
Ever used betel nut, %26.929.024.80.40
Education > 5 y, %22.521.024.10.51
Own TV, %38.332.743.80.04
  • Abbreviations: HCys, homocysteine; HHCys, hyperhomocysteinemia; IQR, interquartile range.

  • aP was from Wilcoxon rank-sum test and χ2 test for sex difference for continuous and categorical variables, respectively.

  • bWhole sample, n = 315; men, n = 160; women, n = 155.

  • cWhole sample, n = 250; men, n = 125; women, n = 125.

  • dWhole sample, n = 318; men, n = 159; women, n = 159.

  • eWhole sample, n = 306; men, n = 154; women, n = 152.

  • fWhole sample, n = 321; men, n = 162; women, n = 159.

  • gPlasma folate < 9 nmol/L.

  • hPlasma vitamin B12 < 151 pmol/L.

  • iPlasma Hcys ≥ 13 μmol/L.

  • jP was from Fisher exact test, as there were only 2 female smokers.