Table 2.

Cox regression HRs and 95% CIs for the association between at-/postdiagnosis ETS exposure and mortality in the LIBCSP women diagnosed with breast cancer in 1996–1997 (N = 1,339).

All-cause mortality (deaths, n = 428)Breast cancer–specific mortality (deaths, n = 126)
ETS exposureAge adjustedMultivariable adjustedaAge adjustedMultivariable adjusteda
At-diagnosis/postdiagnosisDeathsCensoredHR (95% CI)HR (95% CI)DeathsCensoredHR (95% CI)HR (95% CI)
ETS exposure status
 Never/Never791631 (Ref.)1 (Ref.)232191 (Ref.)1 (Ref.)
 Never/Former10181.14 (0.44–2.94)0.94 (0.35–2.58)<524
 Former/Never2515291.03 (0.79–1.35)1.03 (0.78–1.36)697110.93 (0.56–1.54)0.92 (0.55–1.54)
 Former/Former5140.96 (0.21–4.54)0.72 (0.14–3.58)<518
 Former/Current21481.32 (0.72–2.43)1.05 (0.56–1.99)8611.16 (0.43–3.18)0.87 (0.31–2.46)
 Current/Never22431.29 (0.76–2.20)1.19 (0.67–2.09)6581.00 (0.38–2.63)0.88 (0.32–2.42)
 Current/Former14181.99 (0.97–4.09)1.81 (0.87–3.74)6262.20 (0.81–5.97)1.89 (0.68–5.24)
 Current/Current26781.18 (0.70–1.99)1.02 (0.59–1.77)8960.82 (0.33–2.06)0.66 (0.24–1.81)
  • NOTE: LIBCSP participants diagnosed with breast cancer between August 1, 1996, and July 31, 1997, followed-up for vital status through December 31, 2014. Complete-case analyses exclude women who died within 5 years of breast cancer diagnosis (n = 169).

  • aAdjusted for age at diagnosis, BMI, marital status, income, alcohol intake, physical activity, stage, tumor size, nodal involvement, estrogen receptor status, chemotherapy treatment, and postdiagnosis active cigarette smoking status.